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General Information
Symbol
Dmel\egg235
Species
D. melanogaster
Name
FlyBase ID
FBal0212302
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

T24778033A

Reported nucleotide change:

T?A

Comment:

Nucleotide substitution in the splice donor for intron 4 from GT to GA. There is a second base mutation (C to A) in the ninth base of the same intron.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Two nucleotide substitutions at the 5' end of intron 4.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

egg235/Df(2R)Dll-MP transheterozygotes are semi-lethal, display a very low male:female ratio, and the few males die within 2-3 days; egg235/Df(2R)ED4065 transheterozygotes are near lethal and no adult males eclose. egg235/Df(2R)Dll-MP and egg235/Df(2R)ED4065 transheterozygous adults exhibit shaky, uncoordinated movements and held-out wings that are incompletely expanded, as compared to controls; the locomotor and wing phenotypes of egg235/Df(2R)Dll-MP transheterozygotes are more pronounced in males than in females.

89.2% of egg235/Df(2R)Dll-MP females survive to adulthood, but only 27.8% of egg235/Df(2R)Dll-MP males survive to adulthood.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

egg235/+ reduces condensation of polytene chromosome 4 in Su(var)3-96 mutants. The chromosome is often broader and shorter than in wild type.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)