FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pdm2UAS.Tag:HA
Open Close
General Information
Symbol
Dmel\pdm2UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0212606
Feature type
allele
Associated gene
Dmel\pdm2
Associated Insertion(s)
Carried in Construct
P{UAS-pdm2.HA}
Also Known As
UAS-HA:pdm2, UAS-pdm2
Key Links
Transgenic product class
cDNA
(Grosskortenhaus et al., 2006)
wild_type
(Grosskortenhaus et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Grosskortenhaus et al., 2006)
wild_type
(Grosskortenhaus et al., 2006)
Mutagen
in vitro construct
(Grosskortenhaus et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-pdm2.HA}
Cytology
Description

UASt regulatory sequences drive expression of the pdm2 open reading frame (from EST RE34565) tagged at the N-terminal end with Tag:HA.

(Grosskortenhaus et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
pdm2
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of pdm2Scer\UAS.T:Ivir\HA1 using Scer\GAL4wor.PA or Scer\GAL4sca-109-68 delays quiescence of thoracic neuroblast 3-3.

      (Tsuji et al., 2008)

      Embryos expressing pdm2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4pros.PMG have normal U1-U4 neuronal identity. However, these embryos typically have four or more supernumerary U5 neurons within thoracic segments and a similar, but weaker, supernumerary U5 neuron phenotype in abdominal segments.

      Embryos expressing pdm2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4en-e16E have supernumerary U5 neurons and show partial loss of U4 and U3 neurons.

      (Grosskortenhaus et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of hbScer\UAS.cWa and pdm2Scer\UAS.T:Ivir\HA1 in neuroblast NB7-1 under the control of Scer\GAL4en-e16E produces an average of nine U neurons per hemisegment.

      (Tran et al., 2010)

      Co-expression of casScer\UAS.cKa and pdm2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4en-e16E results in embryos which have normal U1/U2 neurons, but show a loss of the U3/U4 neurons and extra U5 neurons.

      Embryos expressing pdm2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4pros.PMG in a cas39/cas39 background have ectopic U4 neurons.

      (Grosskortenhaus et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pdm2Scer\UAS.T:Ivir\HA1
      pdm2UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (6)