FlyBase Allele Report: Dmel\CG11700[EP1384]

General Information

Symbol

Dmel\CG11700^EP1384

Species

D. melanogaster

Name

FlyBase ID

FBal0212635

Feature type

allele

Associated gene

Dmel\CG11700

Associated Insertion(s)

P{EP}CG11700^EP1384

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{EP}CG11700^EP1384

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:6,283,722..6,283,722 [-]

(Warrick et al., 2005)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Machado-Joseph disease

modeled by Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Bilen and Bonini, 2007)

ameliorates tauopathy

modeled by Hsap\MAPT^R406W.UAS

(Bilen and Bonini, 2007)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

CG11700^EP1384/Scer\GAL4^GMR.PU is a non-enhancer of visible phenotype of hid^GMR.PG

(Bilen and Bonini, 2007)

Suppressor of

Statement

Reference

CG11700^EP1384, Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

CG11700^EP1384, Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Hsap\HSPA1L^K71E.UAS, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

CG11700^EP1384, Scer\GAL4^GMR.PU is a suppressor of abnormal neuroanatomy | adult stage phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

CG11700^EP1384, Scer\GAL4^GMR.PF is a suppressor | partially of visible phenotype of Hsap\HSPA1L^K71E.UAS, Scer\GAL4^GMR.PF

(Warrick et al., 2005)

NOT Suppressor of

Statement

Reference

CG11700^EP1384/Scer\GAL4^GMR.PU is a non-suppressor of visible phenotype of hid^GMR.PG

(Bilen and Bonini, 2007)

Scer\GAL4^GMR.PU, CG11700^EP1384/Prosβ6^1.B.UAS is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

CG11700^EP1384/Scer\GAL4^GMR.PU is a non-enhancer of eye phenotype of hid^GMR.PG

(Bilen and Bonini, 2007)

Suppressor of

Statement

Reference

CG11700^EP1384, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

CG11700^EP1384, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Hsap\HSPA1L^K71E.UAS, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

CG11700^EP1384, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

CG11700^EP1384, Scer\GAL4^GMR.PF is a suppressor | partially of eye phenotype of Hsap\HSPA1L^K71E.UAS, Scer\GAL4^GMR.PF

(Warrick et al., 2005)

NOT Suppressor of

Statement

Reference

CG11700^EP1384/Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of hid^GMR.PG

(Bilen and Bonini, 2007)

Scer\GAL4^GMR.PU, CG11700^EP1384/Prosβ6^1.B.UAS is a non-suppressor of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

CG11700^EP1384 is a moderate suppressor of the eye degeneration phenotype caused by expression of Hsap\ATXN3^{tr.Q78.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^GMR.PU.

In the presence of Prosβ6^1.B.Scer\UAS, CG11700^EP1384 cannot suppress the eye degeneration phenotype caused by expression of Hsap\ATXN3^{tr.Q78.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^GMR.PU.

(Bilen and Bonini, 2007)

Co-expression of CR11700^EP1384 partially suppresses the mutant eye phenotype caused by expression of Hsap\HSPA1L^{K71E.Scer\UAS} under the control of Scer\GAL4^GMR.PF.

(Warrick et al., 2005)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG11700^EP1384

CR11700^EP1384

(Bilen and Bonini, 2007)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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