FB2026_02 , released June 18, 2026
Allele: Dmel\Rassf44.2
Open Close
General Information
Symbol
Dmel\Rassf44.2
Species
D. melanogaster
Name
FlyBase ID
FBal0212720
Feature type
allele
Associated gene
Dmel\Rassf
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Polesello et al., 2006)
    Mutagen
    Progenitor genotype
    P{EPgy2}EY02800
    (Polesello et al., 2006)
    Cytology
    Description

    Imprecise excision of the P{EPgy2} element, resulting in a 2120bp deletion that includes the start sites of Rassf transcription and translation.

    (Polesello et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Rassf44.2 flies are less resistant to γ-irradiation than controls.

        (Polesello et al., 2006)

        The body weight of RassfX16/Rassf44.2 flies is around 15% lower than wild-type flies.

        (Polesello et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Partially rescued by

        RassfX16/Rassf44.2 is partially rescued by Rassf+7

        (Polesello et al., 2006)
        Comments

        Expression of a single copy of the Rassf+7 genomic construct significantly rescues the small body weight of RassfX16/Rassf44.2 flies, although weight is not entirely restored to wild-type levels.

        (Polesello et al., 2006)
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Rassf44.2
        dRASSF44.2
        (Polesello et al., 2006, Polesello et al., 2006)
        rassf44.2
        (Zheng et al., 2017)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)