FB2026_02 , released June 18, 2026
Allele: Dmel\RassfX16
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General Information
Symbol
Dmel\RassfX16
Species
D. melanogaster
Name
FlyBase ID
FBal0212717
Feature type
allele
Associated gene
Dmel\Rassf
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Polesello et al., 2006)
Mutagen
P-element activity
(Polesello et al., 2006)
Progenitor genotype
P{EP}RassfGE23517
(Polesello et al., 2006)
Cytology
Description

Excision of the P{EP} element, resulting in a deletion of 932bp of the Rassf gene, starting from the original insertion site.

(Polesello et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      RassfX16 flies are less resistant to γ-irradiation than controls.

      (Polesello et al., 2006)

      The body weight of RassfX16, RassfX16/RassfX36 and RassfX16/Rassf44.2 flies is around 15% lower than wild-type flies. The wing surface area of RassfX16 flies is reduced, while wing hair density is unaffected.

      (Polesello et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      RassfX16 has decreased body size | adult stage phenotype, suppressible | partially by hpo42-48/hpo[+]

      (Polesello et al., 2006)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      RassfX16/RassfX16 is an enhancer of wing phenotype of Scer\GAL4Bx-MS1096, savUAS.Tag:HA

      (Polesello et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of savScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Bx-MS1096 in a RassfX16/RassfX16 background results in a 15% reduction in wing area, while the reduction is only 5% in a wild-type background.

      (Polesello et al., 2006)

      The reduced body mass phenotype of RassfX16 flies is partially suppressed by one copy of hpo42-48.

      (Polesello et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      RassfX16/Rassf44.2 is partially rescued by Rassf+7

      (Polesello et al., 2006)
      Comments

      Expression of a single copy of the Rassf+7 genomic construct significantly rescues the small body weight of RassfX16/Rassf44.2 flies, although weight is not entirely restored to wild-type levels.

      (Polesello et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      RassfX16
      dRASSFX16
      (Polesello et al., 2006, Polesello et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)