FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dscam1A-17.2-19+23.UAS.GFP
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General Information
Symbol
Dmel\Dscam1A-17.2-19+23.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0213038
Feature type
allele
Associated gene
Dmel\Dscam1
Associated Insertion(s)
Carried in Construct
P{UAS-Dscam1.A-17.2-19+23GFP}
Key Links
Transgenic product class
cDNA
(Wang et al., 2004)
wild_type
(Wang et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wang et al., 2004)
wild_type
(Wang et al., 2004)
Mutagen
in vitro construct
(Wang et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Dscam1.A-17.2-19+23GFP}
Cytology
Description

UAS regulatory sequences drive expression of a full-length Dscam1 cDNA, which is tagged at the C-terminal end with GFP. The Dscam1 sequences contain the alternative exons 4.3, 6.36, 9.25 and 17.2. Exon 19 is absent and exon 23 is present.

(Wang et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dscam1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Dscam1A-17.2-19+23.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4ppk.PG induces exuberant presynaptic overgrowth.

      (Kim et al., 2013)

      Scer\GAL4ey-OK107-mediated expression of Dscam1A-17.2-19+23.Scer\UAS.T:Avic\GFP in Dscam1unspecified clones (using the MARCM/GAL80 system) show the multibranch/lobe phenotype in 16% of cases, and a single-branch/neuron phenotype in 11% of cases.

      Scer\GAL4ey-OK107-mediated expression of Dscam1A-17.2-19+23.Scer\UAS.T:Avic\GFP in wild type clones (using the MARCM/GAL80 system) has hardly any effect: axon bifurcation at the peduncle terminus is suppressed in only 3% of cases.

      (Yu et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4ey-OK107/Dscam1A-17.2-19+23.UAS.GFP partially rescues Dscam1unspecified

      (Yu et al., 2009)
      Comments

      Scer\GAL4ey-OK107-mediated expression of Dscam1A-17.2-19+23.Scer\UAS.T:Avic\GFP in Dscam1unspecified clones (using the MARCM/GAL80 system) reduces the multibranch/lobe phenotype from 97% to 16% of cases.

      (Yu et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dscam1A-17.2-19+23.Scer\UAS.T:Avic\GFP
      Dscam1A-17.2-19+23.UAS.GFP
      DscamA-17.2-19+23.Scer\UAS.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (5)