FlyBase Allele Report: Dmel\αSnap[l65]

General Information

Symbol

Dmel\αSnap^l65

Species

D. melanogaster

Name

FlyBase ID

FBal0213066

Feature type

allele

Associated gene

Dmel\αSnap

Associated Insertion(s)

Carried in Construct

Also Known As

SNAP^l65

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

loss of function allele

(Babcock et al., 2004)

Mutagen

ethyl methanesulfonate

(Babcock et al., 2004)

Progenitor genotype

Cytology

Description

A G to A alteration at the first nucleotide of the third intron.

(Babcock et al., 2004)

Nucleotide substitution: G?A.

(Babcock et al., 2004)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3L:20,315,304..20,315,304 [+]

Nucleotide change:

G20315304A

Reported nucleotide change:

G?A

Comment:

G to A mutation in the third intron splice donor site.

(Babcock et al., 2004)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(3L)rdgC-co2)

(Babcock et al., 2004)

lethal - all die during embryonic stage | recessive

(Babcock et al., 2004)

some die during embryonic stage | recessive

(Babcock et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

alphaSnap[+]/αSnap^l65 is an enhancer of short lived | heat sensitive phenotype of comt¹

(Babcock et al., 2015)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

αSnap^l65/+ significantly enhances the shortened lifespan phenotype of comt¹/comt¹ mutants.

(Babcock et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

αSnap^M4

(Babcock et al., 2004)

αSnap^G8

(Babcock et al., 2004)

αSnap^I1

(Babcock et al., 2004)

αSnap^M3

(Babcock et al., 2004)

αSnap^P2

(Babcock et al., 2004)

Rescued by

αSnap^l65 is rescued by αSnap^+t8.9

(Babcock et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

95242

w^*; αSnap^l65/TM6B, P{Ubi-GFP.S65T}PAD2, Tb¹

Notes on Origin

Discoverer

Selected as: a mutant that is lethal in trans to Df(3L)rdgC-co2.

(Babcock et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

SNAP^l65

(Babcock et al., 2004)

Snap^l65

snap^l65

(Babcock et al., 2015)

αSnap^l65

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close