2-day expression of Tbce^GD10779 and Tbce^KK100119 combined, under the control of Scer\GAL4^69B and Gal80[ts] results in a small third instar larval brain with mitotic defects: increased mitotic index with increased mitotic timing; neuroblasts exhibit over-condensed chromosomes, shorter spindles and decreased microtubule densities during metaphase; microtubule re-growth assays reveal that neuroblasts show a severe impairment of microtubule nucleation on the kinetochores and spindle region, while nucleation at the centrosome appeared similar to the controls.

2-day expression of Tbce^GD10779 under the control of Scer\GAL4^69B and Gal80[ts] leads to the third instar larval brain exhibiting increased mitotic index, increased mitotic timing and shorter spindles.

Expression under the control of Scer\GAL4¹⁴⁰⁷ results in loss of neuroblasts in the larval brain associated with increased size of the remaining neuroblasts.

Expression under the control of Scer\GAL4¹⁴⁰⁷ results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.

Expression under the control of Scer\GAL4¹⁴⁰⁷ results in mild defects in the shape of neuroblasts in the larval brain.