2-day expression of Tbce^GD10779 and Tbce^KK100119 combined, under the control of Scer\GAL4^69B and Gal80[ts] results in a small third instar larval brain with mitotic defects: increased mitotic index with increased mitotic timing; neuroblasts exhibit over-condensed chromosomes, shorter spindles and decreased microtubule densities during metaphase; microtubule re-growth assays reveal that neuroblasts show a severe impairment of microtubule nucleation on the kinetochores and spindle region, while nucleation at the centrosome appeared similar to the controls.

2-day expression of Tbce^KK100119 under the control of Scer\GAL4^69B and Gal80[ts] leads to the third instar larval brain exhibiting increased mitotic index, increased mitotic timing and shorter spindles.

Scer\GAL4^69B, Tbce^GD10779, Tbce^KK100119 has abnormal mitotic cell cycle | third instar larval stage phenotype, enhanceable by Scer\GAL4^69B/mad2^KK108038

Scer\GAL4^69B, Tbce^GD10779, Tbce^KK100119 has abnormal mitotic cell cycle | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^69B/mad2^KK108038