FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Vps28UAS.cSa
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General Information
Symbol
Dmel\Vps28UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Sevrioukov
FlyBase ID
FBal0215634
Feature type
allele
Associated gene
Dmel\Vps28
Associated Insertion(s)
Carried in Construct
P{UAS-Vps28.S}
Also Known As
UAS-vps28
Key Links
Transgenic product class
wild_type
(Sevrioukov et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Sevrioukov et al., 2005)
Mutagen
in vitro construct
(Sevrioukov et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Vps28.S}
Cytology
Description

UASt regulatory sequences drive expression of Vps28.

(Sevrioukov et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Vps28
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Vps28Scer\UAS.cSa under the control of Scer\GAL4c564 does not lead to significant changes in the average adult fat body cell size, as compared to controls.

      (Neyen et al., 2016)

      Vps28k16503 males that express Vps28Scer\UAS.cSa under the control of Scer\GAL4arm.PS are infertile and possess very few motile sperm. These males show a defect at sperm individualization, where the appearance of actin cones is disorganised compared to wild-type males.

      (Sevrioukov et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PU/Vps28UAS.cSa rescues Vps28B9

      (Zhang et al., 2014)

      Vps28UAS.cSa/Scer\GAL4arm.PS rescues Vps28k16503/Df(2R)CA53

      (Sevrioukov et al., 2005)
      Partially rescues

      Vps28UAS.cSa/Scer\GAL4arm.PS partially rescues Vps28k16503

      (Sevrioukov et al., 2005)
      Comments

      Expression of Vps28Scer\UAS.cSa under the control of Scer\GAL4arm.PS rescues the lethality and female sterility of Vps28k16503 mutants, however it does not rescue male sterility.

      (Sevrioukov et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Vps28Scer\UAS.cSa
      Vps28UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Sevrioukov
      Secondary FlyBase IDs
        References (3)