FlyBase Allele Report: Dmel\Prosα6[LA1]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\Prosα6^LA1

General Information

Symbol

Dmel\Prosα6^LA1

Species

D. melanogaster

Name

FlyBase ID

FBal0215844

Feature type

allele

Associated gene

Associated Insertion(s)

P{lacW}Prosα6^LA1

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Fluegel et al., 2006)

Progenitor genotype

Associated Insertion(s)

P{lacW}Prosα6^LA1

Cytology

Description

P{lacW} insertion in the 5' untranslated region of Pros35.

(Fluegel et al., 2006)

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

reporter enzyme

Tagged with

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of first instar larval stage (with Df(2L)J2)

(Fluegel et al., 2006)

lethal - all die before end of first instar larval stage | recessive

(Fluegel et al., 2006)

some die during first instar larval stage (with Df(2L)J2)

(Fluegel et al., 2006)

some die during first instar larval stage | recessive

(Fluegel et al., 2006)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

(Fluegel et al., 2006)

Rescued by

Prosα6^LA1 is rescued by Prosα6^+t8

(Fluegel et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Comments

Complements: NPC1^57A.

(Fluegel et al., 2006)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Pros35^LA1

(Fluegel et al., 2006)

Prosα6^LA1

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections