FlyBase Allele Report: Dmel\salm[B1164]

General Information

Symbol

Dmel\salm^B1164

Species

D. melanogaster

Name

FlyBase ID

FBal0216420

Feature type

allele

Associated gene

Dmel\salm

Associated Insertion(s)

P{Mae-UAS.6.11}salm^B1164

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{Mae-UAS.6.11}salm^B1164

Cytology

Description

Insertion approximately 2kb of the salm locus, such that expression from the Scer\UAS sites present in the insertion (using a Scer\GAL4 driver) results in overexpression of the salm locus.

(Grieder et al., 2009)

Allele components

Component

Use(s)

Inserted element

P{Mae-UAS.6.11}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^dpp.blk1

(Grieder et al., 2009, Grieder et al., 2007, Grieder et al., 2007)

Phenotype Manifest In

anterior crossvein, with Scer\GAL4^dpp.blk1

(Grieder et al., 2007)

leg, with Scer\GAL4^dpp.blk1

(Grieder et al., 2009)

leg | proximal, with Scer\GAL4^dpp.blk1

(Grieder et al., 2007)

mesonotum | ectopic, with Scer\GAL4^dpp.blk1

(Grieder et al., 2009)

mesothoracic leg disc, with Scer\GAL4^dpp.blk1

(Grieder et al., 2009)

mesothoracic preepisternum, with Scer\GAL4^dpp.blk1

(Grieder et al., 2009, Grieder et al., 2007, Grieder et al., 2007)

wing, with Scer\GAL4^dpp.blk1

(Grieder et al., 2009)

wing | proximal, with Scer\GAL4^dpp.blk1

(Grieder et al., 2007)

Detailed Description

Statement

Reference

Expression of salm^B1164 under the control of Scer\GAL4^dpp.blk1 results in an outgrowth on the sternopleura of the fly. This outgrowth looks morphologically like notum tissue. The flies also have wing and leg defects.

Mesothoracic leg discs expressing salm^B1164 under the control of Scer\GAL4^dpp.blk1 show extra growth in dorsal cells.

(Grieder et al., 2009)

Expression of B1164^B1164 under the control of Scer\GAL4^dpp.blk1 results in a notum-like outgrowth at the sternopleura.

(Grieder et al., 2007)

Expression of B1164^B1164 under the control of Scer\GAL4^dpp.blk1 results in a notum-like outgrowth at the sternopleura. In addition, the proximal parts of the wings and legs are shortened. In the wing, this can result in the anterior crossvein being absent.

(Grieder et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

The "B1164" line contains two insertions; one at 32F and one at 35D.

(Grieder et al., 2007)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

B1164^B1164

salm^B1164

(Grieder et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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