FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pufA459
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General Information
Symbol
Dmel\pufA459
Species
D. melanogaster
Name
FlyBase ID
FBal0217036
Feature type
allele
Associated gene
Dmel\puf
Associated Insertion(s)
PBac{5HPw+}pufA459
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - molecular evidence

    (Li et al., 2013)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    PBac{5HPw+}pufA459
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        A few homozygotes mutants survive to adulthood; they are short-lived and male sterile.

        (Li et al., 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        pufA459 is a suppressor of eye phenotype of MycUAS.cZa, Scer\GAL4GMR.PU

        (Li et al., 2013)

        pufA459 is a suppressor of eye phenotype of MycUAS.cZa, Scer\GAL4GMR.PU, ago1

        (Li et al., 2013)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Precise excision of the PBac element reverts the lethality, sterility and short life span phenotypes.

        (Li et al., 2013)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CG5794A459
        pufA459
        (Li et al., 2013)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)