FlyBase Allele Report: Dmel\Asap[KG03963]

General Information

Symbol

Dmel\Asap^KG03963

Species

D. melanogaster

Name

FlyBase ID

FBal0217250

Feature type

allele

Associated gene

Dmel\Asap

Associated Insertion(s)

P{SUPor-P}Asap^KG03963

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}Asap^KG03963

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{SUPor-P}

insertional mutagenesis tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:8,122,426..8,122,426 [-]

(Johnson et al., 2011, FlyBase Curators, 2008-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Asap^KG03963/CG30372[+] is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of retina phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of ommatidium phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of primary pigment cell phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of secondary pigment cell phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of tertiary pigment cell phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of cone cell phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap^KG03963/CG30372[+] is an enhancer of interommatidial precursor cell phenotype of Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF

(Johnson et al., 2011)

Asap1[+]/Asap^KG03963 is an enhancer of embryonic/larval cuticle phenotype of baz⁴

(Shao et al., 2010)

Asap1[+]/Asap^KG03963 is an enhancer of embryonic/larval cuticle phenotype of baz^G0484

(Shao et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

The eye mis-patterning phenotype resulting from the co-expression of Arf51F^GD13822 with Dcr-2^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF is significantly enhanced in Asap1^KG03963 heterozygotes. The number of correctly patterned secondary and tertiary cell is reduced. The total number of interommatidial precursor cells (IPCs) does not differ markedly from the wild-type number of 12, indicating that the enhancement is due to specifically to increased disorder in IPC patterning. Additionally, errors in the placement of three bristle groups about each ommatidium and errors in primary pigment cell and cone cell patterning and ommatidial rotation are modestly enhanced.

The ommatidial patterning errors resulting from the expression of cindr^{dsRNA.PC.PD.Scer\UAS} via Scer\GAL4^GMR.PF are strongly increased in Asap1^KG03963 heterozygotes.

(Johnson et al., 2011)

The cuticle phenotype of dead embryos derived from baz⁴/+ embryos derived from a cross of baz⁴/+ females to wild-type males is enhanced if the females also carry one copy of Asap1^KG03963.

The cuticle phenotype of dead embryos derived from baz^G0484/+ embryos derived from a cross of baz^G0484/+ females to wild-type males is enhanced if the females also carry one copy of Asap1^KG03963.

(Shao et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

13356

y¹ w^67c23; P{SUPor-P}Asap^KG03963/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Asap1^KG03963

Asap^KG03963

CG30372^KG03963

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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