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General Information
Symbol
Dmel\NimC4UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0218197
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UASsimu
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of NimC4 tagged with GFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Expression of NimC4Scer\UAS.T:Avic\GFP under the control of Scer\GAL4repo.PU partially rescues the phagocytosis defects seen in repo03702 mutant embryos. The morphology and localisation of the glia still appear abnormal and the cells are overloaded with apoptotic particles. However, although the total volume of apoptotic particles in the CNS remains the same as in repo03702 mutant embryos alone, a higher proportion have been engulfed by phagocytes in the rescue embryos.

Co-expression of NimC4Scer\UAS.T:Avic\GFP and drprI.Scer\UAS under the control of Scer\GAL4repo.PU fully rescues the phagocytosis defects seen in repo03702 mutant embryos.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of NimC4ΔEMI-NIM2.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4repo rescues the defects in the engulfment of apoptotic neurons seen in the CNS of NimC4KO mutant embryos.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
NimC4Scer\UAS.T:Avic\GFP
NimC4UAS.GFP
nimC4Scer\UAS.T:Avic\GFP
Name Synonyms
Secondary FlyBase IDs
    References (5)