FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\subCT.UASp.EGFP
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General Information
Symbol
Dmel\subCT.UASp.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0218570
Feature type
allele
Associated gene
Dmel\sub
Associated Insertion(s)
Carried in Construct
P{UASp-sub.CT}
Key Links
Transgenic product class
inframe_deletion
(Jang et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Jang et al., 2007)
Mutagen
in vitro construct
(Jang et al., 2007)
Progenitor genotype
Carried in construct
P{UASp-sub.CT}
Cytology
Description

UASp regulatory sequences drive expression of the C-terminal portion of sub, which is tagged with EGFP.

(Jang et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
sub
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      spindle microtubule & oocyte, with Scer\GAL4VP16.nanos.UTR

      (Jang et al., 2007)
      Detailed Description
      Statement
      Reference

      Females expressing subCT.Scer\UAS.P\T.T:Avic-EGFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 show a high level of X chromosome meiotic nondisjunction compared to control females. 8/10 oocytes studied have abnormal microtubule organisation such as tripolar, monopolar or frayed spindles or spindles lacking interpolar microtubules.

      Expression of subCT.Scer\UAS.P\T.T:Avic-EGFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in sub1794/+ females results in reduced numbers of progeny.

      Expression of subCT.Scer\UAS.P\T.T:Avic-EGFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in sub1794/sub1 females results in sterility.

      (Jang et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      subCT.Scer\UAS.P\T.T:Avic-EGFP
      subCT.UASp.EGFP
      subCT.UASp.T:Avic-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)