FlyBase Allele Report: Dmel\bdg[GMREP]

General Information

Symbol

Dmel\bdg^GMREP

Species

D. melanogaster

Name

FlyBase ID

FBal0219011

Feature type

allele

Associated gene

Dmel\bdg

Associated Insertion(s)

P{Mae-GMR.EP}bdg^GMREP

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{Mae-GMR.EP}bdg^GMREP

Cytology

Description

Insertion within an intron.

(Rawls et al., 2007)

Allele components

Component

Use(s)

Inserted element

P{Mae-GMR.EP}

misexpression element

Regulatory region(s)

GMR

engineered transcription regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity

(Rawls et al., 2007)

Phenotype Manifest In

eye photoreceptor cell

(Rawls et al., 2007)

ommatidium

(Rawls et al., 2007)

Detailed Description

Statement

Reference

Heterozygous flies have normal eyes.

12% of ommatidia have polarity defects in homozygous flies. 82% of these polarity defects being due to problems in the specification of the R3 and R4 cell fates, resulting in symmetric ommatidia. An additional 8% are missing photoreceptors. The external surface of the eye remains smooth in homozygous flies, and the lattice is perfectly maintained due to wild-type rotation of the mutant ommatidia.

(Rawls et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

bdg^GMREP has abnormal planar polarity phenotype, suppressible by dsh¹/dsh[+]

(Rawls et al., 2007)

bdg^GMREP has abnormal planar polarity phenotype, suppressible by pk[+]/pk^unspecified

(Rawls et al., 2007)

bdg^GMREP has abnormal planar polarity phenotype, suppressible by stan[+]/stan^frz3

(Rawls et al., 2007)

bdg^GMREP has abnormal planar polarity phenotype, suppressible by dgo[+]/dgo³⁸⁰

(Rawls et al., 2007)

bdg^GMREP has abnormal planar polarity phenotype, suppressible by Vang^stbm-6/Vang[+]

(Rawls et al., 2007)

NOT suppressed by

Statement

Reference

bdg^GMREP has abnormal planar polarity phenotype, non-suppressible by fz[+]/fz¹⁹

(Rawls et al., 2007)

Enhancer of

Statement

Reference

bdg[+]/bdg^GMREP is an enhancer of abnormal planar polarity phenotype of dsh¹

(Rawls et al., 2007)

bdg[+]/bdg^GMREP is an enhancer of abnormal planar polarity phenotype of stan^frz3

(Rawls et al., 2007)

NOT Enhancer of

Statement

Reference

bdg[+]/bdg^GMREP is a non-enhancer of abnormal planar polarity phenotype of pk^unspecified

(Rawls et al., 2007)

Suppressor of

Statement

Reference

bdg[+]/bdg^GMREP is a suppressor of abnormal planar polarity phenotype of Vang^sev.PR

(Rawls et al., 2007)

bdg[+]/bdg^GMREP is a suppressor of abnormal planar polarity phenotype of dgo³⁸⁰

(Rawls et al., 2007)

NOT Suppressor of

Statement

Reference

bdg[+]/bdg^GMREP is a non-suppressor of abnormal planar polarity phenotype of pk^unspecified

(Rawls et al., 2007)

Phenotype Manifest In

Suppressed by

Statement

Reference

bdg^GMREP has ommatidium phenotype, suppressible by Vang^stbm-6/Vang[+]

(Rawls et al., 2007)

bdg^GMREP has ommatidium phenotype, suppressible by dsh¹/dsh[+]

(Rawls et al., 2007)

bdg^GMREP has ommatidium phenotype, suppressible by pk[+]/pk^unspecified

(Rawls et al., 2007)

bdg^GMREP has ommatidium phenotype, suppressible by stan[+]/stan^frz3

(Rawls et al., 2007)

bdg^GMREP has ommatidium phenotype, suppressible by dgo[+]/dgo³⁸⁰

(Rawls et al., 2007)

NOT suppressed by

Statement

Reference

bdg^GMREP has ommatidium phenotype, non-suppressible by fz[+]/fz¹⁹

(Rawls et al., 2007)

Enhancer of

Statement

Reference

bdg[+]/bdg^GMREP is an enhancer of ommatidium phenotype of dsh¹

(Rawls et al., 2007)

bdg[+]/bdg^GMREP is an enhancer of ommatidium phenotype of stan^frz3

(Rawls et al., 2007)

NOT Enhancer of

Statement

Reference

bdg[+]/bdg^GMREP is a non-enhancer of ommatidium phenotype of pk^unspecified

(Rawls et al., 2007)

Suppressor of

Statement

Reference

bdg[+]/bdg^GMREP is a suppressor of ommatidium phenotype of Vang^sev.PR

(Rawls et al., 2007)

bdg[+]/bdg^GMREP is a suppressor of ommatidium phenotype of dgo³⁸⁰

(Rawls et al., 2007)

NOT Suppressor of

Statement

Reference

bdg[+]/bdg^GMREP is a non-suppressor of ommatidium phenotype of pk^unspecified

(Rawls et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

The ommatidial polarity defects caused by Vang^sev.PR are significantly suppressed by one copy of bdg^GMREP.

bdg^GMREP dominantly enhances the ommatidial polarity defects of dsh¹ and stan^frz3 mutants.

The ommatidial polarity defects caused by pk^unspecified are not modified by one copy of bdg^GMREP.

The ommatidial polarity defects caused by dgo³⁸⁰ are suppressed by one copy of bdg^GMREP.

(Rawls et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

bdg^GMREP

(Rawls et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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