FlyBase Allele Report: Dmel\Chc[+t14.3]

General Information

Symbol

Dmel\Chc^+t14.3

Species

D. melanogaster

Name

FlyBase ID

FBal0219619

Feature type

allele

Associated gene

Dmel\Chc

Associated Insertion(s)

Carried in Construct

P{Chc.+t14.3}

Also Known As

pgChc+

Key Links

Genomic Maps

JBrowse

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Eun et al., 2008)

Progenitor genotype

Carried in construct

P{Chc.+t14.3}

Cytology

Description

14.3kb AvrII-SacII genomic fragment containing Chc.

(Eun et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

Chc

Encoded product / tool

Chc

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

rescue_region

X:15,825,204..15,839,489 [-]

Linked to:

SstII-AvrII restriction fragment

Comment:

Position of rescue fragment on reference sequence inferred by FlyBase curator.

(Eun et al., 2008)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Chc^+t14.3 is a suppressor | partially of lethal phenotype of aux^K47/aux^D128

(Banks et al., 2011)

lqf^GFP/Chc^+t14.3 is a suppressor | partially of lethal phenotype of aux^K47/aux^D128

(Banks et al., 2011)

Chc^+t14.3 is a suppressor of visible phenotype of aux^K47/aux^D128

(Eun et al., 2008)

Phenotype Manifest In

Suppressor of

Statement

Reference

Chc^+t14.3 is a suppressor | partially of eye phenotype of aux^K47/aux^D128

(Banks et al., 2011)

lqf^GFP/Chc^+t14.3 is a suppressor of eye phenotype of aux^K47/aux^D128

(Banks et al., 2011)

lqf^GFP/Chc^+t14.3 is a suppressor of ommatidium phenotype of aux^K47/aux^D128

(Banks et al., 2011)

Chc^+t14.3 is a suppressor | partially of ommatidium phenotype of aux^K47/aux^D128

(Banks et al., 2011, Eun et al., 2008)

Chc^+t14.3 is a suppressor of wing blade phenotype of aux^K47/aux^D128

(Eun et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Addition of Chc^+t14.3 to a aux^D128/aux^K47 background increases the eclosion frequency of adults markedly. The mutant eye phenotype of those rescued animals is suppressed somewhat (from 8% to 28% wild-type ommatidia).

aux^D128/aux^K47 mutant flies carrying both Chc^+t14.3 and lqf^{+t16240.T:Avic\GFP} exhibit remarkably normal-appearing eyes (97% wild-type ommatidia). However, no increase in viability is seen in these flies above the level observed with lqf^{+t16240.T:Avic\GFP} alone.

(Banks et al., 2011)

Chc^+t14.3 completely suppresses the mutant wing phenotype of aux^D128/aux^K47 flies and significantly suppresses the mutant facet phenotype of aux^D128/aux^K47 flies.

(Eun et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Chc^+t14.3

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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