FlyBase Allele Report: Dmel\Sod2[JF01989]

General Information

Symbol

Dmel\Sod2^JF01989

Species

D. melanogaster

Name

FlyBase ID

FBal0219975

Feature type

allele

Associated gene

Dmel\Sod2

Associated Insertion(s)

Carried in Construct

P{TRiP.JF01989}

Also Known As

uas-Sod2-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.1.15)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.1.15)

Mutagen

in vitro construct

(Perkins et al., 2009.1.15)

Progenitor genotype

Carried in construct

P{TRiP.JF01989}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.1.15)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF01989

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates amyotrophic lateral sclerosis type 8

modeled by Vap33^P58S.cRa.UAS

(Chaplot et al., 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

follicle cell | somatic clone, with Scer\GAL4^Tub.PU

(Uttekar et al., 2024)

mitochondrion | somatic clone, with Scer\GAL4^Tub.PU

(Uttekar et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^Tub.PU/Sod2^JF01989 is a suppressor | partially of abnormal cell size | somatic clone | oogenesis phenotype of Drp1^KG03815

(Uttekar et al., 2024)

Scer\GAL4^Tub.PU/Sod2^JF01989 is a suppressor | partially of increased size | somatic clone | oogenesis phenotype of Drp1^KG03815

(Uttekar et al., 2024)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^Tub.PU/Sod2^JF01989 is a non-enhancer of female germ cell nucleus | somatic clone phenotype of Drp1^KG03815

(Uttekar et al., 2024)

Suppressor of

Statement

Reference

Scer\GAL4^Tub.PU/Sod2^JF01989 is a suppressor | partially of follicle cell | somatic clone phenotype of Drp1^KG03815

(Uttekar et al., 2024)

Scer\GAL4^Tub.PU/Sod2^JF01989 is a suppressor | partially of mitochondrion | somatic clone phenotype of Drp1^KG03815

(Uttekar et al., 2024)

Scer\GAL4^Tub.PU/Sod2^JF01989 is a suppressor | partially of apical part of cell | somatic clone phenotype of Drp1^KG03815

(Uttekar et al., 2024)

NOT Suppressor of

Statement

Reference

Sod2^JF01989, Scer\GAL4^FRT.Act5C is a non-suppressor of larval fat cell | somatic clone phenotype of Pex11g^UAS.Tag:FLAG, Scer\GAL4^FRT.Act5C

(Liu and He, 2024)

Sod2^JF01989, Scer\GAL4^FRT.Act5C is a non-suppressor of lipid droplet | somatic clone | larval stage phenotype of Pex11g^UAS.Tag:FLAG, Scer\GAL4^FRT.Act5C

(Liu and He, 2024)

Scer\GAL4^Tub.PU/Sod2^JF01989 is a non-suppressor of female germ cell nucleus | somatic clone phenotype of Drp1^KG03815

(Uttekar et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

25969

y¹ v¹; P{TRiP.JF01989}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Sod2^JF01989

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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