FlyBase Allele Report: Dmel\Den1[EX9]

General Information

Symbol

Dmel\Den1^EX9

Species

D. melanogaster

Name

FlyBase ID

FBal0220531

Feature type

allele

Associated gene

Dmel\Den1

Associated Insertion(s)

Carried in Construct

Also Known As

DEN1^null

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Chan et al., 2008)

Mutagen

P-element activity

(Chan et al., 2008)

Progenitor genotype

P{EPgy2}EY04455

(Chan et al., 2008)

Cytology

Description

Imprecise excision of the P{EPgy2}EY04455 insertion, resulting in a deletion of the entire Den1 transcription unit.

(Chan et al., 2008)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Chan et al., 2008)

viable

(Chan et al., 2008)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Den1^EX9 is a suppressor of increased cell death phenotype of rpr^GMR.PU

(Broemer et al., 2010)

Den1^EX9 is a suppressor of increased cell death phenotype of hid^GMR.PG

(Broemer et al., 2010)

Den1^EX9/Den1[+] is a suppressor | partially of lethal phenotype of Nedd8^EP2063/Nedd8^AN015

(Chan et al., 2008)

Den1^EX9/Den1[+] is a suppressor | partially of lethal phenotype of Nedd8^EP2063/Nedd8^AN024

(Chan et al., 2008)

Phenotype Manifest In

Suppressor of

Statement

Reference

Den1^EX9 is a suppressor of eye phenotype of rpr^GMR.PU

(Broemer et al., 2010)

Den1^EX9 is a suppressor of eye phenotype of hid^GMR.PG

(Broemer et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Eye cell death observed in W^GMR.PG flies is suppressed in a Den1^EX9 mutant background.

Eye cell death observed in rpr^GMR.PU flies is suppressed in a Den1^EX9 mutant background.

(Broemer et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

DEN1^EX9

(Broemer et al., 2010)

DEN1^null

(Kim et al., 2017, Chan et al., 2008, Chan et al., 2008)

Den1^EX9

EX9

(Chan et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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