FlyBase Allele Report: Dmel\rpr[GMR.PU]

General Information

Symbol

Dmel\rpr^GMR.PU

Species

D. melanogaster

Name

glass multimer reporter construct of Unknown

FlyBase ID

FBal0240692

Feature type

allele

Associated gene

Dmel\rpr

Associated Insertion(s)

Carried in Construct

P{GMR-rpr.U}

Also Known As

GMR-rpr

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{GMR-rpr.U}

Cytology

Description

GMR regulatory sequences drive expression of rpr.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

rpr

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Hwangbo et al., 2016, Chuang et al., 2014, Arya and Lakhotia, 2008, Copeland et al., 2007)

visible, with Scer\GAL4^GMR.PU

(Chinchore et al., 2012)

visible | adult stage

(Koerver et al., 2016)

Phenotype Manifest In

eye

(Hwangbo et al., 2016, Chuang et al., 2014, Arya and Lakhotia, 2008, Copeland et al., 2007)

eye, with Scer\GAL4^GMR.PU

(Chinchore et al., 2012)

eye | adult stage

(Koerver et al., 2016)

Detailed Description

Statement

Reference

rpr^GMR.PU leads to small eyes with apoptotic phenotypes in the retina.

(Hwangbo et al., 2016)

Expression of rpr^GMR.PU results in small and rough eye phenotype in adult flies.

(Koerver et al., 2016)

Expression of rpr^GMR.PU results in a reduced eye size compared to controls and severe disruption to the ommatidia.

(Chuang et al., 2014)

Ectopic expression of one copy of rpr^GMR.PU under the control of Scer\GAL4^GMR.PU in flies causes eye ablation.

(Chinchore et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

rpr^GMR.PU has visible phenotype, non-enhanceable by ec^EPΔ4

(Copeland et al., 2007)

rpr^GMR.PU has visible phenotype, non-enhanceable by ec^SF1.GMR

(Copeland et al., 2007)

Suppressed by

Statement

Reference

rpr^GMR.PU has visible phenotype, suppressible | partially by DCAF12^GD10933/Scer\GAL4^GMR.PU

(Hwangbo et al., 2016)

rpr^GMR.PU has visible | adult stage phenotype, suppressible | partially by Duba^GD11813/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

rpr^GMR.PU has visible | adult stage phenotype, suppressible | partially by Duba^KK108478/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

rpr^GMR.PU has visible | adult stage phenotype, suppressible | partially by Duba¹⁰⁷/Duba[+]

(Koerver et al., 2016)

rpr^GMR.PU has visible phenotype, suppressible | partially by Hsap\LRRK2^UAS.cCa/Scer\GAL4^GMR.PU

(Chuang et al., 2014)

rpr^GMR.PU has visible phenotype, suppressible by BacA\p35^GMR.PH/Scer\GAL4^GMR.PU

(Chinchore et al., 2012)

rpr^GMR.PU has increased cell death phenotype, suppressible by Den1^RNAi.UAS.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

rpr^GMR.PU has increased cell death phenotype, suppressible by CSN5^NIG.14884R/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

rpr^GMR.PU has increased cell death phenotype, suppressible by CG1503^RNAi.UAS.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

rpr^GMR.PU has increased cell death phenotype, suppressible by Den1^EX9

(Broemer et al., 2010)

rpr^GMR.PU has visible phenotype, suppressible | partially by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

NOT suppressed by

Statement

Reference

rpr^GMR.PU has visible phenotype, non-suppressible by ec^EPΔ4

(Copeland et al., 2007)

rpr^GMR.PU has visible phenotype, non-suppressible by ec^SF1.GMR

(Copeland et al., 2007)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

rpr^GMR.PU has eye phenotype, non-enhanceable by ec^EPΔ4

(Copeland et al., 2007)

rpr^GMR.PU has eye phenotype, non-enhanceable by ec^SF1.GMR

(Copeland et al., 2007)

Suppressed by

Statement

Reference

rpr^GMR.PU has eye phenotype, suppressible | partially by DCAF12^GD10933/Scer\GAL4^GMR.PU

(Hwangbo et al., 2016)

rpr^GMR.PU has eye | adult stage phenotype, suppressible | partially by Duba^GD11813/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

rpr^GMR.PU has eye | adult stage phenotype, suppressible | partially by Duba^KK108478/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

rpr^GMR.PU has eye | adult stage phenotype, suppressible | partially by Duba¹⁰⁷/Duba[+]

(Koerver et al., 2016)

rpr^GMR.PU has eye phenotype, suppressible | partially by Hsap\LRRK2^UAS.cCa/Scer\GAL4^GMR.PU

(Chuang et al., 2014)

rpr^GMR.PU has ommatidium phenotype, suppressible | partially by Hsap\LRRK2^UAS.cCa/Scer\GAL4^GMR.PU

(Chuang et al., 2014)

rpr^GMR.PU has eye phenotype, suppressible by BacA\p35^GMR.PH/Scer\GAL4^GMR.PU

(Chinchore et al., 2012)

rpr^GMR.PU has eye phenotype, suppressible by Den1^RNAi.UAS.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

rpr^GMR.PU has eye phenotype, suppressible by CSN5^NIG.14884R/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

rpr^GMR.PU has eye phenotype, suppressible by CG1503^RNAi.UAS.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

rpr^GMR.PU has eye phenotype, suppressible by Den1^EX9

(Broemer et al., 2010)

rpr^GMR.PU has eye phenotype, suppressible | partially by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

NOT suppressed by

Statement

Reference

rpr^GMR.PU has eye phenotype, non-suppressible by ec^EPΔ4

(Copeland et al., 2007)

rpr^GMR.PU has eye phenotype, non-suppressible by ec^SF1.GMR

(Copeland et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of DCAF12^GD10933 driven by Scer\GAL4^GMR.PU partially suppresses apoptotic eye phenotypes in rpr^GMR.PU flies.

(Hwangbo et al., 2016)

The strongly reduced eye size characteristic for adult flies expressing rpr^GMR.PU is partially reverted by expression of either Duba^GD11813 or Duba^KK108478 under the control of Scer\GAL4^GMR.PU or by combination with the Duba¹⁰⁷ allele in heterozygous state.

(Koerver et al., 2016)

Eye cell death observed in rpr^GMR.PU flies is suppressed by expression of Den1^VDRC.cUa under the control of Scer\GAL4^GMR.PF.

Eye cell death observed in rpr^GMR.PU flies is suppressed by expression of CSN5^NIG.14884R under the control of Scer\GAL4^GMR.PF.

Eye cell death observed in rpr^GMR.PU flies is suppressed by expression of CG1503^VDRC.cUa under the control of Scer\GAL4^GMR.PF.

Eye cell death observed in rpr^GMR.PU flies is suppressed in a Den1^EX9 mutant background.

(Broemer et al., 2010)

Xenogenetic Interactions

Statement

Reference

Expression of Hsap\LRRK2^Scer\UAS.cCa under the control of Scer\GAL4^GMR.PU partially suppresses the eye phenotypes seen upon expression of rpr^GMR.PU.

(Chuang et al., 2014)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

rpr^GMR.PU

Name Synonyms

glass multimer reporter construct of Unknown

Secondary FlyBase IDs

References (11)

Report Sections

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