FlyBase Allele Report: Dmel\Bx[D124]

General Information

Symbol

Dmel\Bx^D124

Species

D. melanogaster

Name

FlyBase ID

FBal0220815

Feature type

allele

Associated gene

Dmel\Bx

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Biryukova et al., 2009)

Progenitor genotype

P{EPgy2}EY01065

(Biryukova et al., 2009)

Cytology

Description

Imprecise excision of the P{EPgy2}EY01065 insertion, resulting in a deletion that includes Bx 3' UTR sequences (proximal deletion breakpoint is within the Bx 3'UTR.

(Biryukova et al., 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible (with Bx^MS1096)

(Biryukova et al., 2009)

visible | dominant

(Biryukova et al., 2009)

Phenotype Manifest In

wing

(Biryukova et al., 2009)

wing (with Bx^MS1096)

(Biryukova et al., 2009)

wing margin

(Biryukova et al., 2009)

Detailed Description

Statement

Reference

Heterozygotes have strong wing defects.

Bx^D124/Y flies have wing margin defects. The wing defects caused by Bx^D124 are partially suppressed if the flies also carry Bx^MS1096.

(Biryukova et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Bx^D124 has visible phenotype, enhanceable by mir-9a^J22/mir-9a[+]

(Biryukova et al., 2009)

Suppressed by

Statement

Reference

Bx^MS1096/Bx^D124 has visible phenotype, suppressible | partially by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

Phenotype Manifest In

Enhanced by

Statement

Reference

Bx^D124 has wing margin phenotype, enhanceable by mir-9a^J22/mir-9a[+]

(Biryukova et al., 2009)

Suppressed by

Statement

Reference

Bx^MS1096/Bx^D124 has wing phenotype, suppressible | partially by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

The wing margin phenotype seen in Bx^D124/Y flies is enhanced by mir-9a^J22/+.

The wing defects seen in Bx^D124/Bx^MS1096 flies are partially suppressed by expression of mir-9a^Scer\UAS.cBa under the control of Scer\GAL4^Bx-MS1096.

(Biryukova et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Bx^D124

(Biryukova et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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