FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(var)205MB11439
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General Information
Symbol
Dmel\Su(var)205MB11439
Species
D. melanogaster
Name
FlyBase ID
FBal0221441
Feature type
allele
Associated gene
Dmel\Su(var)205
Associated Insertion(s)
Mi{ET1}Su(var)205MB11439
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{ET1}Su(var)205MB11439
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{ET1}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        exacerbates  Alzheimer's disease
        modeled by Hsap\MAPTR406W.UAS
        (Frost et al., 2014)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        Su(var)205MB11439/Su(var)205[+] is an enhancer of increased cell death phenotype of Hsap\MAPTR406W.UAS, Scer\GAL4elav.PU

        (Frost et al., 2014)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        Su(var)205MB11439/Su(var)205[+] is an enhancer of neuron phenotype of Hsap\MAPTR406W.UAS, Scer\GAL4elav.PU

        (Frost et al., 2014)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        Heterozygous Su(var)205MB11439 enhances the Scer\GAL4elav.PU>Hsap\MAPTR406W.Scer\UAS induced neuronal apoptosis.

        (Frost et al., 2014)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        HP1αMB11439
        (Park et al., 2023)
        Su(var)205ET
        (Frost et al., 2014)
        Su(var)205MB11439
        (Bellen, 2009.5.28)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)