FB2026_02 , released June 18, 2026
Allele: Dmel\Mnt2
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General Information
Symbol
Dmel\Mnt2
Species
D. melanogaster
Name
FlyBase ID
FBal0221793
Feature type
allele
Associated gene
Dmel\Mnt
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Loo et al., 2005)
Mutagen
Delta2-3 transposase
(Loo et al., 2005)
Progenitor genotype
P{EP}EP1559
(Loo et al., 2005)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion of Mnt sequences. The deletion removes the exon containing the translational start codons of both the Mnt isoform that contains both the SID and bHLHZ domains and of the Mnt ΔZIP isoform, but does not extend to the exon containing the translational start codon of the Mnt ΔZIP isoform.

(Loo et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies show an increase n ommatidial size compared to controls.

      (Steiger et al., 2008)

      Homozygous embryos show no significant difference in hatching rates compared to controls. No defects are seen in larval molting, pupation or eclosion in homozygotes.

      Mutant adult males are 12% heavier than wild-type controls. Mutant males have 10 fewer wing trichomes in a defined area of the adult wing, indicative of an increase in cell size.

      Mutant females show a significant reduction in adult life span compared to controls. There is also a reduction in the maximal life expectancy (90% mortality) compared to controls.

      (Loo et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Mnt2 is a non-suppressor of ommatidium phenotype of MycUAS.cZa, Scer\GAL4GMR.PF

      (Steiger et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The eye phenotypes (apoptosis and increased ommatidial size) caused by expression of three copies of dmScer\UAS.cZa under the control of Scer\GAL4GMR.PF are not qualitatively altered by Mnt2/Y.

      (Steiger et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mnt2
      (Steiger et al., 2008)
      dmnt2
      (Loo et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)