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General Information
Symbol
Dmel\spenKK100153
Species
D. melanogaster
Name
FlyBase ID
FBal0230599
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adulthood-generated midgut clones expressing spenKK100153 under the control of Scer\GAL4Tub.PU have more cells and show a severe increase in the number of Intestinal stem cells (Dl-positive), as compared to control clones.

Adulthood-induced expression of spenKK100153 (using Gal80[ts] for the temporal control of expression) under the control of either Scer\GAL4esg.PU, Scer\GAL4Su(H).GBE, Scer\GAL4pros-V1, Scer\GAL4NP0001, or Scer\GAL4esg.PU plus Scer\GAL80Su(H).GBE, leads to a significant increase in the number of mitotic cells per posterior midgut, as compared to control; adulthood-induced under the control of Scer\GAL4esg.PU, Scer\GAL4Su(H).GBE, or Scer\GAL4esg.PU plus Scer\GAL80Su(H).GBE, but not under the control of Scer\GAL4pros-V1 or Scer\GAL4NP0001, also leads to a significant increase in the density of stem cells in the posterior midgut, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
spenKK100153
Name Synonyms
Secondary FlyBase IDs
    References (2)