FlyBase Allele Report: Dmel\Yeats2[KK100444]

General Information

Symbol

Dmel\Yeats2^KK100444

Species

D. melanogaster

Name

FlyBase ID

FBal0230753

Feature type

allele

Associated gene

Dmel\Yeats2

Associated Insertion(s)

Carried in Construct

P{KK100444}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK100444}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK100444

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of familial adult myoclonic epilepsy 4

CEA

(Lo Piccolo et al., 2024)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior | adult stage, with Scer\GAL4^nSyb.PP

(Lo Piccolo et al., 2024)

abnormal stress response | larval stage, with Scer\GAL4^elav.PU

(Lo Piccolo et al., 2026)

abnormal stress response | larval stage, with Scer\GAL4^elav-C155

(Lo Piccolo et al., 2024)

bang sensitive, with Scer\GAL4^elav.PU

(Lo Piccolo et al., 2026)

bang sensitive, with Scer\GAL4^nSyb.PP

(Lo Piccolo et al., 2024)

decreased cell number | adult stage, with Scer\GAL4^Ddc.PL

(Lo Piccolo et al., 2026)

decreased rate of adult locomotory behavior, with Scer\GAL4^Ddc.PL

(Lo Piccolo et al., 2026)

decreased rate of adult locomotory behavior, with Scer\GAL4^elav-C155

(Lo Piccolo et al., 2024)

decreased rate of adult locomotory behavior, with Scer\GAL4^nSyb.PP

(Lo Piccolo et al., 2024)

decreased rate of adult locomotory behavior, with Scer\GAL4^VGlut1-OK371

(Lo Piccolo et al., 2026)

decreased rate of movement | adult stage, with Scer\GAL4^nSyb.PP

(Lo Piccolo et al., 2024)

paralytic | larval stage | heat sensitive, with Scer\GAL4^elav-C155

(Lo Piccolo et al., 2024)

short lived, with Scer\GAL4^da.G32

(Lo Piccolo et al., 2024)

Phenotype Manifest In

adult dopaminergic neuron | decreased number, with Scer\GAL4^Ddc.PL

(Lo Piccolo et al., 2026)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^elav.PU, Yeats2^KK100444 has bang sensitive phenotype, suppressible by Orai^E180A.UAS, Scer\GAL4^elav.PU

(Lo Piccolo et al., 2026)

NOT suppressed by

Statement

Reference

Scer\GAL4^elav.PU, Yeats2^KK100444 has abnormal stress response | larval stage phenotype, non-suppressible by Scer\GAL4^elav.PU/trp^HMJ23244

(Lo Piccolo et al., 2026)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v105606

P{KK100444}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

D12^KK100444

Yeats2^KK100444

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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