FlyBase Allele Report: Dmel\Su(H)[KK101550]

General Information

Symbol

Dmel\Su(H)^KK101550

Species

D. melanogaster

Name

FlyBase ID

FBal0231342

Feature type

allele

Associated gene

Dmel\Su(H)

Associated Insertion(s)

Carried in Construct

P{KK101550}

Also Known As

UAS-Su(H)-RNAi, UAS-Su(H) RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101550}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101550

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of alcohol use disorder

CEA

(Petruccelli et al., 2018)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Scer\GAL4^ato.3.6

(Langen et al., 2013)

increased cell number | larval stage, with Scer\GAL4^insc.PU

(Bala et al., 2026)

increased cell number | third instar larval stage, with Scer\GAL4^Antp-21

(Small et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Su(H)^KK101550 under the control of Scer\GAL4^Antp-21 leads to an increase in the number of lamellocytes in the anterior lymph gland lobe of third instar larvae, but does not affect the size or cell number in the niche.

(Small et al., 2014)

Expression of Su(H)^KK101550 under the control of Scer\GAL4^ato.3.6 results in clustering of dorsal cluster neuron axons. There is a significant increase in the number of medulla axons compared to wild type.

(Langen et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^insc.PU, Su(H)^KK101550 has increased cell number | larval stage phenotype, enhanceable by brm^HM04019/Scer\GAL4^insc.PU

(Bala et al., 2026)

Enhancer of