FlyBase Allele Report: Dmel\Syx7[KK101990]

General Information

Symbol

Dmel\Syx7^KK101990

Species

D. melanogaster

Name

FlyBase ID

FBal0231587

Feature type

allele

Associated gene

Dmel\Syx7

Associated Insertion(s)

Carried in Construct

P{KK101990}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101990}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101990

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate, with Scer\GAL4^rn.PU

(Romão et al., 2021, Boone et al., 2016)

Phenotype Manifest In

epithelium, with Scer\GAL4^NP1624

(Berns et al., 2014)

female germline cyst, with Scer\GAL4^NP1624

(Berns et al., 2014)

Detailed Description

Statement

Reference

Expression of Syx7^KK101990 under the control of Scer\GAL4^rn.PU leads to long delay in pupariation compared to controls.

(Boone et al., 2016)

Scer\GAL4^tj-NP1624-mediated expression results in the transformation of the normal germline cyst epithelial monolayer into two or more cell layers.

(Berns et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^rn.PU, Syx7^KK101990 has abnormal developmental rate phenotype, suppressible | partially by Ilp8^GD1670, Scer\GAL4^rn.PU

(Romão et al., 2021)

Scer\GAL4^rn.PU, Syx7^KK101990 has abnormal developmental rate phenotype, suppressible | partially by Scer\GAL4^rn.PU/sd^KK108877

(Boone et al., 2016)

Scer\GAL4^rn.PU, Syx7^KK101990 has abnormal developmental rate phenotype, suppressible | partially by yki^KK109756/Scer\GAL4^rn.PU

(Boone et al., 2016)

NOT suppressed by

Statement

Reference

Scer\GAL4^rn.PU, Syx7^KK101990 has abnormal developmental rate phenotype, non-suppressible by Rh3^KK103758, Scer\GAL4^rn.PU

(Boone et al., 2016)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The marked delay in pupariation characteristic for larvae expressing Syx7^KK101990 under the control of Scer\GAL4^rn.PU can be partially suppressed by co-expression of either sd^KK108877 or yki^KK109756 but not Rh3^KK103758.

(Boone et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v107264

P{KK101990}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Syx7^KK101990

(Ochi et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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