FlyBase Allele Report: Dmel\Ilp8[GD1670]

General Information

Symbol

Dmel\Ilp8^GD1670

Species

D. melanogaster

Name

FlyBase ID

FBal0200584

Feature type

allele

Associated gene

Dmel\Ilp8

Associated Insertion(s)

Carried in Construct

P{GD1670}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD1670}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD1670

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Adults expressing Ilp8^GD1670 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

1670

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Ilp8^GD1670, Scer\GAL4^rn.PU is a suppressor | partially of abnormal developmental rate phenotype of Scer\GAL4^rn.PU, Syx7^KK101990

(Romão et al., 2021)

NOT Suppressor of

Statement

Reference

Ilp8^GD1670, Scer\GAL4^ap-md544 is a non-suppressor of abnormal developmental rate phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Romão et al., 2021)

upd1^JF03149/Ilp8^GD1670, Scer\GAL4^ap-md544 is a non-suppressor of abnormal developmental rate phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Romão et al., 2021)

Scer\GAL4^ap-md544, upd3^GD6811/Ilp8^GD1670 is a non-suppressor of abnormal developmental rate phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Romão et al., 2021)

Ilp8^GD1670, Scer\GAL4^Act.PU is a non-suppressor of neoplasia | somatic clone | third instar larval stage phenotype of BacA\p35^UAS.cHa, Scer\GAL4^Act.PU, Snr1^HMS00363

(Xie et al., 2017)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Ilp8^GD1670, Scer\GAL4^Act.PU is a non-suppressor of wing disc | somatic clone | third instar larval stage phenotype of BacA\p35^UAS.cHa, Scer\GAL4^Act.PU, Snr1^HMS00363

(Xie et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The aggressive tissue overgrowth observed in third instar larval wing discs carrying somatic (flip-out) clones simultaneously expressing Snr1^HMS00363 and BacA\p35^Scer\UAS.cHa driven by Scer\GAL4^Act.PU cannot be suppressed by co-expression Ilp8^GD1670.

(Xie et al., 2017)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v9420

w¹¹¹⁸; P{GD1670}v9420

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

1670

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG14059^GD1670

Ilp8^GD1670

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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