FlyBase Allele Report: Dmel\Bub3[GD9924]

General Information

Symbol

Dmel\Bub3^GD9924

Species

D. melanogaster

Name

FlyBase ID

FBal0198851

Feature type

allele

Associated gene

Dmel\Bub3

Associated Insertion(s)

Carried in Construct

P{GD9924}

Also Known As

UAS-bub3^RNAi, bub3-i, UAS-bub3-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD9924}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD9924

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of cancer

CEA

(Barrio et al., 2023)

CEA with BacA\p35^UAS.cHa

(Muzzopappa et al., 2017)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of cancer

is ameliorated by upd3^HMS00646

(Barrio et al., 2023)

is exacerbated by BacA\p35^UAS.cHa

(Barrio et al., 2023)

is ameliorated by bsk^DN.UAS.cUa

(Barrio et al., 2023)

is ameliorated by dome^GD14494

(Barrio et al., 2023)

is ameliorated by hop^JF01268

(Barrio et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal DNA repair | larval stage, with Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

abnormal size | adult stage, with Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

increased cell death | larval stage, with Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

visible, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

trichogen cell, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

wing disc posterior compartment, with Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

Detailed Description

Statement

Reference

The expression of Bub3^GD9924 under the control of Scer\GAL4^e22c leads to X chromosome aneuploidy and to a significant increase in the larval wing disc posterior compartment of both females and males; loss of the X chromosome was never detected in males. Expression under the control of Scer\GAL4^ey.PH leads to a small decrease in eye size, as compared to controls.

(Clemente-Ruiz et al., 2016)

Adults expressing Bub3^GD9924 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

Expression under the control of Scer\GAL4^pnr-MD237 results in loss of bristles on the notum in 60-70% of the Scer\GAL4^pnr-MD237 expression domain.

Expression under the control of Scer\GAL4^pnr-MD237 results in bristle morphology defects on the notum in 20-30% of the Scer\GAL4^pnr-MD237 expression domain.

(Mummery-Widmer et al., 2009)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

9924

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has neoplasia | larval stage phenotype, enhanceable by stg^UAS.cNa, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by msl-1^GD1242, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by msl-2^GD14745, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by msl-2^GD14745, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by mei-41^GD4258, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by mei-41^GD4258, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by grp^KK108548, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by grp^KK108548, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by okr^KK107487, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by okr^KK107487, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by DNAlig4^KK101734, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by DNAlig4^KK101734, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by msl-1^HMS01930, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by lic^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by lic^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by p38b^NIG.7393R, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by p38b^NIG.7393R, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by CG44247^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | female by msl-1^HMS01930, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by CG44247^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Stat92E^GD4492, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by Stat92E^GD4492, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by Stat92E^GD4492, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Stat92E^KK100519, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by Stat92E^KK100519, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by Stat92E^KK100519, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Stat92E^85C9/Stat92E[+]

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by Stat92E^85C9/Stat92E[+]

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by Stat92E^85C9/Stat92E[+]

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by upd3^Δ/upd3^Δ/upd2^Δ3-62/upd2^Δ3-62

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable by upd3^Δ/upd3^Δ/upd2^Δ3-62/upd2^Δ3-62

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable by upd3^Δ/upd3^Δ/upd2^Δ3-62/upd2^Δ3-62

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^e22c has increased cell death | larval stage phenotype, enhanceable by lic^RNAi.UAS.cUa, Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | male by Sxl^HMS00609, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, enhanceable | male by Sxl^HMS00609, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, enhanceable | female by msl-1^GD1242, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

NOT Enhanced by

Statement

Reference

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, non-enhanceable by p53^GD4483, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, non-enhanceable by p53^GD4483, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has abnormal size | adult stage phenotype, non-enhanceable by p53^H159N.UAS.Ex, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has visible phenotype, non-enhanceable by p53^H159N.UAS.Ex, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^e22c has abnormal DNA repair | larval stage phenotype, non-enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

Suppressed by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has increased size | larval stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^e22c

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has increased size | larval stage phenotype, suppressible by wg^HMS00794, Scer\GAL4^e22c

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has increased size | larval stage phenotype, suppressible by wg^KK108857, Scer\GAL4^e22c

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by upd1^JF03149/upd3^HM05061, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by dome^ΔCYT.UAS, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by dome^ΔTMCYT.UAS, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by upd3^Δ

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by Stat92E^RNAi.lexAop/Ecol\lexA^phtm.PU

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible | partially by dome^GD14494, Scer\GAL4^P0206, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by mir-ban^{sponge.UAS.DsRed(Unk)}, Scer\GAL4^P0206, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible | partially by Ilp8^KO

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has increased cell number | larval stage phenotype, suppressible by rpr^UAS.C/Scer\GAL4^He.PZ

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has neoplasia | larval stage phenotype, suppressible by trbl^UAS.cMa, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal size | larval stage phenotype, suppressible by dome^ΔCYT.UAS, Scer\GAL4^ap-md544

(Clemente-Ruiz et al., 2016)

NOT suppressed by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by NLaz^GD12709, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by NLaz^KK107553, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by NLaz^NW5

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by upd3^GD6811, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by upd3^HM05061, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by upd1^JF03149, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by hop^JF01268, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by dome^KK104700, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by upd1^JF03149/Ilp8^GD1670, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by upd3^GD6811/Ilp8^GD1670, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by upd3^GD6811/NLaz^KK107553, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by NLaz^KK107553/Ilp8^KK112161, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by dome^GD14494, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by mir-ban^{sponge.UAS.DsRed(Unk)}, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by wg^HMS00794, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by wg^KK108857, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by Ilp8^GD1670, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, non-suppressible by Ilp8^KK112161, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has neoplasia | larval stage phenotype, non-suppressible by rpr^UAS.C/Scer\GAL4^He.PZ

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has neoplasia | larval stage phenotype, non-suppressible by rpr^lexAop.cSa/Ecol\lexA^GMR15B03

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has increased cell number | larval stage phenotype, non-suppressible by rpr^lexAop.cSa/Ecol\lexA^GMR15B03

(Muzzopappa et al., 2017)

Other

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has increased cell number | larval stage phenotype

(Romão et al., 2021, Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has increased size | larval stage phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^Mef2.PU, Scer\GAL4^ap-md544, upd3^HM05061 has abnormal developmental rate phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544, Scer\GAL4^upd3.PA, upd3^HM05061 has abnormal developmental rate phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^He.PZ, Scer\GAL4^ap-md544, upd3^HM05061 has abnormal developmental rate phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has increased body size | larval stage phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has neoplasia | larval stage phenotype

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has abnormal size | larval stage phenotype

(Clemente-Ruiz et al., 2016)

Phenotype Manifest In

Enhanced by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc phenotype, enhanceable by stg^UAS.cNa, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by msl-2^GD14745, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by mei-41^GD4258, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by grp^KK108548, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by msl-1^HMS01930, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by okr^KK107487, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by DNAlig4^KK101734, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by lic^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by p38b^NIG.7393R, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by CG44247^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Stat92E^GD4492, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Stat92E^KK100519, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Stat92E^85C9/Stat92E[+]

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | male by Sxl^HMS00609, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable by upd3^Δ/upd3^Δ/upd2^Δ3-62/upd2^Δ3-62

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^e22c has wing disc posterior compartment phenotype, enhanceable by lic^RNAi.UAS.cUa, Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, enhanceable | female by msl-1^GD1242, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

NOT Enhanced by

Statement

Reference

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, non-enhanceable by p53^GD4483, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^ey.PH has eye phenotype, non-enhanceable by p53^H159N.UAS.Ex, Scer\GAL4^ey.PH

(Clemente-Ruiz et al., 2016)

Bub3^GD9924, Scer\GAL4^e22c has wing disc posterior compartment phenotype, non-enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^e22c

(Clemente-Ruiz et al., 2016)

Suppressed by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has wing disc | larval stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^e22c

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has wing disc | larval stage phenotype, suppressible by wg^HMS00794, Scer\GAL4^e22c

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has wing disc | larval stage phenotype, suppressible by wg^KK108857, Scer\GAL4^e22c

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has embryonic/larval hemocyte | increased number | larval stage phenotype, suppressible by rpr^UAS.C/Scer\GAL4^He.PZ

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc phenotype, suppressible by trbl^UAS.cMa, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc dorsal compartment phenotype, suppressible by dome^ΔCYT.UAS, Scer\GAL4^ap-md544

(Clemente-Ruiz et al., 2016)

NOT suppressed by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc phenotype, non-suppressible by rpr^UAS.C/Scer\GAL4^He.PZ

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc phenotype, non-suppressible by rpr^lexAop.cSa/Ecol\lexA^GMR15B03

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has myoblast | increased number | larval stage phenotype, non-suppressible by rpr^lexAop.cSa/Ecol\lexA^GMR15B03

(Muzzopappa et al., 2017)

Other

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has embryonic/larval hemocyte | increased number | larval stage phenotype

(Romão et al., 2021, Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c has wing disc | larval stage phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc | larval stage phenotype

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has myoblast | increased number | larval stage phenotype

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc phenotype

(Muzzopappa et al., 2017)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544 has wing disc dorsal compartment phenotype

(Clemente-Ruiz et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The co-expression of Bub3^GD9924 and BacA\p35^UAS.cHa under the control of Scer\GAL4^ap-md544 induces wing disc neoplasia which, when transplanted, can form solid tumors in the host; in both wing discs and allografts there is amplification of the resident myoblast population, as well as accumulation of circulating hemocytes. The same tumor induction and hemocyte recruitment occurs if expression is only induced in wing disc transplants (expression induction is controlled by Gal80[ts] and temperature-shift); hemocyte ablation on the host (by expressing rpr^UAS.C under the control of Scer\GAL4^He.PZ) does not suppress the tumor-like growth; myoblast ablation on the host (by expressing rpr^lexAop.cSa under the control of Ecol\lexA^GMR15B03) does not suppress the tumor-like growth.