FlyBase Allele Report: Dmel\tkv[KK102319]

General Information

Symbol

Dmel\tkv^KK102319

Species

D. melanogaster

Name

FlyBase ID

FBal0231725

Feature type

allele

Associated gene

Dmel\tkv

Associated Insertion(s)

Carried in Construct

P{KK102319}

Also Known As

UAS-Tkv-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102319}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102319

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm, with Scer\GAL4^P2.4.Pdf

(Beckwith et al., 2013)

increased cell death | embryonic stage, with Scer\GAL4^how-24B

(Yang and Su, 2011)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of tkv^KK102319 under the control of Scer\GAL4^P2.4.Pdf leads to an approximate 60% drop in rhythmicity.

(Beckwith et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

tkv^KK102319/Scer\GAL4^NP5130 is a suppressor of increased cell number | adult stage phenotype of mir-958^KO

(Mukherjee et al., 2021)

Scer\GAL4^how-24B/tkv^KK102319 is a suppressor of increased cell death | embryonic stage phenotype of raw¹

(Yang and Su, 2011)

Phenotype Manifest In

Suppressor of

Statement

Reference

tkv^KK102319/Scer\GAL4^NP5130 is a suppressor of adult midgut epithelium phenotype of mir-958^KO

(Mukherjee et al., 2021)

Scer\GAL4^how-24B/tkv^KK102319 is a suppressor of embryonic cardioblast phenotype of raw¹

(Yang and Su, 2011)

Scer\GAL4^how-24B/tkv^KK102319 is a suppressor of embryonic pericardial cell phenotype of raw¹

(Yang and Su, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v105834

P{KK102319}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

tkv^KK102319

(Hertenstein et al., 2021)

tkv^dsRNA

(Luo et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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