FlyBase Allele Report: Dmel\Fatp1[KK104809]

General Information

Symbol

Dmel\Fatp1^KK104809

Species

D. melanogaster

Name

FlyBase ID

FBal0233215

Feature type

allele

Associated gene

Dmel\Fatp1

Associated Insertion(s)

Carried in Construct

P{KK104809}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK104809}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK104809

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased fecundity | progressive, with Scer\GAL4^Desat1.PB

(Poidevin et al., 2024)

female sterile, with Scer\GAL4^Desat1.PB

(Poidevin et al., 2024)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of abnormal neuroanatomy | somatic clone | adult stage phenotype of Marf^B

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of abnormal neuroanatomy | somatic clone | adult stage phenotype of sicily^E

(Liu et al., 2017)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Fatp1^KK104809, Scer\GAL4^ninaE.PT is a non-enhancer of photoreceptor neuron | adult stage phenotype of Lsd-1^UAS.EGFP, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Fatp1^KK104809, Scer\GAL4^ninaE.PT is a non-enhancer of lipid droplet | adult stage | increased number phenotype of Lsd-1^UAS.EGFP, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Suppressor of

Statement

Reference

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of adult optic lobe glial cell | somatic clone phenotype of Marf^B

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of lipid droplet | somatic clone | adult stage phenotype of Marf^B

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of photoreceptor | somatic clone | adult stage | progressive phenotype of Marf^B

(Liu et al., 2017)

Scer\GAL4^54C/Fatp1^KK104809 is a suppressor of adult optic lobe glial cell | cell non-autonomous phenotype of ND-42^ninaE.GD6220

(Liu et al., 2017)

Scer\GAL4^54C/Fatp1^KK104809 is a suppressor of lipid droplet | cell non-autonomous | adult stage phenotype of ND-42^ninaE.GD6220

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^elav.PLu is a suppressor of adult optic lobe glial cell | cell non-autonomous phenotype of ND-42^ninaE.GD6220

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^elav.PLu is a suppressor of lipid droplet | cell non-autonomous | adult stage phenotype of ND-42^ninaE.GD6220

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of adult optic lobe glial cell | somatic clone phenotype of sicily^E

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of lipid droplet | somatic clone | adult stage phenotype of sicily^E

(Liu et al., 2017)

Fatp1^KK104809/Scer\GAL4^ey.PU is a suppressor of photoreceptor | somatic clone | adult stage | progressive phenotype of sicily^E

(Liu et al., 2017)

NOT Suppressor of

Statement

Reference

Fatp1^KK104809, Scer\GAL4^ninaE.PT is a non-suppressor of photoreceptor neuron | adult stage phenotype of Lsd-1^UAS.EGFP, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Fatp1^KK104809, Scer\GAL4^ninaE.PT is a non-suppressor of lipid droplet | increased number | adult stage phenotype of Lsd-1^UAS.EGFP, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

The accumulation of lipid droplets in glial cells in the vicinity of adult photoreceptor neurons expressing ND-42^ninaE.GD6220 is ameliorated by the expression of Fatp^KK104809 when driven by either Scer\GAL4^54C or Scer\GAL4^elav.PLu.

Expression of Fatp^KK104809 in the ey>flip whole-eye clones mutant for either sicily^E or Marf^B ameliorates the lipid droplet accumulation in retinal glial cells in adult flies and also improves the photoreceptor degeneration phenotype.

(Liu et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100124

P{KK104809}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Fatp1^KK104809

Fatp^KK104809

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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