FlyBase Allele Report: Dmel\Phae1[KK106428]

General Information

Symbol

Dmel\Phae1^KK106428

Species

D. melanogaster

Name

FlyBase ID

FBal0234244

Feature type

allele

Associated gene

Dmel\Phae1

Associated Insertion(s)

Carried in Construct

P{KK106428}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK106428}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK106428

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

larval central nervous system | heat sensitive, with Scer\GAL4^elav-C155

(Matsumura et al., 2025)

Detailed Description

Statement

Reference

The expression of Phae1^KK106428 under the control of Scer\GAL4^c564 has no obvious affect on the inflammatory response to Gram-positive bacterial infection, but leads to a minor ectopic inflammatory response in basal (non-infected) conditions, as compared to controls.

(Kumar et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Phae1^KK106428 is rescued by Phae1^UAS.cMa/Scer\GAL4^nSyb.PP

(Matsumura et al., 2025)

Not rescued by

Phae1^KK106428 is not rescued by Phae1^UAS.cMa/Scer\GAL4^repo

(Matsumura et al., 2025)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v105269

P{KK106428}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG16996^KK106428

Phae1^KK106428

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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