FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\VGlut1KK107498
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General Information
Symbol
Dmel\VGlut1KK107498
Species
D. melanogaster
Name
FlyBase ID
FBal0234968
Feature type
allele
Associated gene
Dmel\VGlut1
Associated Insertion(s)
Carried in Construct
P{KK107498}
Also Known As
UAS-VGlutRNAi, UAS-VGLUT RNAi, UAS-vGlut-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK107498}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK107498
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of VGlutKK107498 under the control of Scer\GAL4GMR27G01 in adults significantly reduces 24-hour associative olfactory water-reward memory, compared to controls, with no effect on odor acuity or water preference; a significant reduction in 24-hour memory is also observed when a Gal80[ts] transgene is used to restrict expression to the adult stage.

      (Shyu et al., 2017)

      Expression of VGlutKK107498 under the control of Scer\GAL4VT000765 or Scer\GAL4VT041043 significantly reduces 3-hour aversive olfactory anaesthesia-resistant memory (ARM), compared to controls; this is also the case when a Gal80[ts] transgene is used to restrict expression to the adult stage; ARM is further reduced when Scer\GAL4VT000765 and Scer\GAL4VT041043 are simultaneously used to drive expression of VGlutKK107498.

      (Yang et al., 2016)

      Expression of VGlutKK107498 under the control of Scer\GAL4Act.PU has no significant effect on green-light avoidance in larvae.

      (Liu et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ethyl butyrate induced habituation in flies expressing TrpA1Ecol\lexAop.T:SV40\nls2 under the control of Ecol\lexAGH146.T:Scer\GAL4-GAD is greatly reduced in the presence of a VGlutKK107498 transgene (expressed under the control of Scer\GAL4NP1227).

      (Sudhakaran et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      VGlut1KK107498
      VGlutKK107498
      Name Synonyms
      Secondary FlyBase IDs
        References (14)