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General Information
Symbol
Scer\GAL4VT041043
Species
S. cerevisiae
Name
FlyBase ID
FBal0307501
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
VT41043-Gal4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 1334 base pair fragment from the flanking non-coding or intronic region of side-IV is fused upstream of a Drosophila synthetic core promoter (DSCP) followed by sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Blocking protein synthesis (using Rcom\RA[cs2.UAS] at 30[o]C) for the full 24 h, or the 4-16 h interval, but not shorter intervals beginning at the 4 h timepoint, nor other 12 h intervals, between spaced, but not massed, training and testing in Scer\GAL4VT041043 neurons, significantly impairs aversive olfactory long term memory in adults, compared to controls; there is no effect when protein synthesis is instead blocked for 24 h prior to training.

Acute inhibition of endocytosis (using shi1.UAS at 32[o]C) in Scer\GAL4VT041043 neurons during testing, 24 h after spaced, but not massed, training significantly impairs aversive olfactory long term memory in adults, compared to controls; this effect is not seen when inhibition occurs during training instead; there is no effect of this inhibition on short term memory.

Inhibition (using shi1.UAS at 31[o]C) of Scer\GAL4VT041043 cells in adults during testing only, but not consolidation only, significantly reduces 3-hour aversive olfactory anaesthesia-resistant memory, compared to controls, with no effect on odor or shock avoidance.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4VT041043
Name Synonyms
Secondary FlyBase IDs
    References (4)