FlyBase Allele Report: Dmel\Hipk[KK107857]

General Information

Symbol

Dmel\Hipk^KK107857

Species

D. melanogaster

Name

FlyBase ID

FBal0235219

Feature type

allele

Associated gene

Dmel\Hipk

Associated Insertion(s)

Carried in Construct

P{KK107857}

Also Known As

UAS-hipk^RNAi, UAS-hipk-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK107857}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK107857

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^ey.PH

(Dewald et al., 2014)

visible, with Scer\GAL4^ey.PH

(Dewald et al., 2014)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Dewald et al., 2014)

Detailed Description

Statement

Reference

The eyes of flies expressing Scer\GAL4^ey.PH>hipk^KK107857 show reduces size compared with wild-type.

(Dewald et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Hipk^KK107857, Scer\GAL4^ey.PH has visible phenotype, enhanceable by Df(2R)NCX8/+

(Dewald et al., 2014)

Hipk^KK107857, Scer\GAL4^ey.PH has abnormal size phenotype, enhanceable by Df(2R)NCX8/+

(Dewald et al., 2014)

Suppressed by

Statement

Reference

Hipk^KK107857, Scer\GAL4^ey.PH has visible phenotype, suppressible by spen[+]/spen³

(Dewald et al., 2014)

Hipk^KK107857, Scer\GAL4^ey.PH has abnormal size phenotype, suppressible by spen[+]/spen³

(Dewald et al., 2014)

Suppressor of

Statement

Reference

Scer\GAL4^Hml.Δ/Hipk^KK107857 is a suppressor of melanotic mass phenotype | adult stage phenotype of hop^Tum

(Tettweiler et al., 2019)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Hml.Δ/Hipk^KK107857 is a non-suppressor of lethal | heat sensitive phenotype of hop^Tum

(Tettweiler et al., 2019)

Phenotype Manifest In

Enhanced by

Statement

Reference

Hipk^KK107857, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Df(2R)NCX8/+

(Dewald et al., 2014)

Suppressed by

Statement

Reference

Hipk^KK107857, Scer\GAL4^ey.PH has eye phenotype, suppressible by spen[+]/spen³

(Dewald et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygous spen³ suppresses the reduced eye-size phenotype of Scer\GAL4^ey.PH>hipk^KK107857.

Df(2R)NCX8 enhances the reduced eye-size phenotype of Scer\GAL4^ey.PH>hipk^KK107857.

(Dewald et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Hipk^KK107857 rescues Hipk^UAS.Tag:HA

(Blaquiere et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108254

P{KK107857}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hipk^KK107857

hipk^KK107857

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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