FlyBase Allele Report: Dmel\Patj[KK110089]

General Information

Symbol

Dmel\Patj^KK110089

Species

D. melanogaster

Name

FlyBase ID

FBal0236641

Feature type

allele

Associated gene

Dmel\Patj

Associated Insertion(s)

Carried in Construct

P{KK110089}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK110089}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK110089

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell size, with Scer\GAL4^NP0001

(Wen et al., 2017)

Phenotype Manifest In

adult midgut epithelium, with Scer\GAL4^NP0001

(Wen et al., 2017)

Detailed Description

Statement

Reference

The expression of Patj^KK110089 under the control of Scer\GAL4^{Myo31DF-NP0001} leads to the adult midgut epithelium presenting aberrant morphology and a severe increase in the average cell size, as compared to controls.

(Wen et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Patj^KK110089, Scer\GAL4^NP0001 has increased cell size phenotype, non-enhanceable by Atg9^HMS01246, Scer\GAL4^NP0001

(Wen et al., 2017)

NOT Enhancer of

Statement

Reference

Patj^KK110089, Scer\GAL4^NP0001 is a non-enhancer of increased cell size phenotype of Atg9^HMS01246, Scer\GAL4^NP0001

(Wen et al., 2017)

NOT Suppressor of

Statement

Reference

Patj^KK110089, Scer\GAL4^repo.PU is a non-suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Patj^KK110089, Scer\GAL4^repo.PU is a non-suppressor of neoplasia | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Patj^KK110089, Scer\GAL4^NP0001 has adult midgut epithelium phenotype, non-enhanceable by Atg9^HMS01246, Scer\GAL4^NP0001

(Wen et al., 2017)

NOT Enhancer of

Statement

Reference

Patj^KK110089, Scer\GAL4^NP0001 is a non-enhancer of adult midgut epithelium phenotype of Atg9^HMS01246, Scer\GAL4^NP0001

(Wen et al., 2017)

NOT Suppressor of

Statement

Reference

Patj^KK110089, Scer\GAL4^repo.PU is a non-suppressor of larval brain | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Patj^KK110089, Scer\GAL4^repo.PU is a non-suppressor of larval brain neuropil glial cell | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of Atg9^HMS01246 and Patj^KK110089 under the control of Scer\GAL4^{Myo31DF-NP0001} does not enhance the increased midgut cell size resulting from either single expression.

(Wen et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v101877

P{KK110089}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Patj^KK110089

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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