FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DreddKK110428
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General Information
Symbol
Dmel\DreddKK110428
Species
D. melanogaster
Name
FlyBase ID
FBal0236850
Feature type
allele
Associated gene
Dmel\Dredd
Associated Insertion(s)
Carried in Construct
P{KK110428}
Also Known As
UAS-Dredd RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK110428}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK110428
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing DreddKK110428 under the control of Scer\GAL4Cg.PA results in a significantly reduced resistance to starvation and decreased lipid storage in the fat body of starved adult flies.

      (Molaei et al., 2019)

      Expression of DreddKK110428 under the control of Scer\GAL4GMR.PF does not affect eye development.

      (Nandi et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      DreddKK110428, Scer\GAL4GMR.PF is a non-enhancer of eye phenotype of AcnUAS.cNa, Scer\GAL4GMR.PF

      (Nandi et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of DreddKK110428 in the developing eye does not affect the eye roughness seen upon expression of AcnScer\UAS.cNa under the control of Scer\GAL4GMR.PF.

      (Nandi et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      DreddKK110428
      Name Synonyms
      Secondary FlyBase IDs
        References (7)