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General Information
Symbol
Dmel\AcnUAS.cNa
Species
D. melanogaster
Name
FlyBase ID
FBal0301140
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Acnwt
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of wild-type Acn coding sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of AcnScer\UAS.cNa under the control of Scer\GAL4GMR.PF results in a mildly rough eye. This phenotype is enhanced by an elevated temperature (28[o]C).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
NOT Enhanced by
Statement
Reference
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Scer\GAL4GMR.PF-driven expression of Akt1Scer\UAS.Exel enhances the rough eye phenotype of the AcnScer\UAS.cNa transgene.

Expression of Dcp-1GD10729 enhances the rough eye phenotype and reduces the overall eye size in flies expressing AcnScer\UAS.cNa under the control of Scer\GAL4GMR.PF.

Expression of DreddKK110428 in the developing eye does not affect the eye roughness seen upon expression of AcnScer\UAS.cNa under the control of Scer\GAL4GMR.PF.

Expression of DroncGD12376 in the developing eye does not affect the eye roughness seen upon expression of AcnScer\UAS.cNa under the control of Scer\GAL4GMR.PF.

Knockdown of Atg1 through expression of Atg1GD7149 under the control of Scer\GAL4GMR.PF suppresses the AcnScer\UAS.cNa-induced rough eye phenotype.

Knockdown of Atg7 through expression of Atg7GD11671 under the control of Scer\GAL4GMR.PF suppresses the AcnScer\UAS.cNa-induced rough eye phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
AcnScer\UAS.cNa
AcnUAS.cNa
Name Synonyms
Secondary FlyBase IDs
    References (3)