FlyBase Allele Report: Dmel\yki[S168A.UAS.EGFP,Tag:HA]

The expression of yki^{S168A.UAS.EGFP,Tag:HA} under the control of Scer\GAL4^Mef2.PR leads to indirect flight muscle atrophy during pupal development (after 32h APF); fibers are shorter than in controls due to premature compaction from 24h APF; fiber hyper-compaction at 32h APF coincides with a chaotic organization of the myofibrils.

(Kaya-Çopur et al., 2021)

Expressing yki^{S168A.UAS.EGFP,Tag:HA} under the control of Scer\GAL4^GMR.PFa induces an abnormal overgrowth of the eye; in agreement, the eye disc shows increased numbers of mitotic cells in the GMR-positive region, as compared to controls.

(Yeom et al., 2020)

Expressing yki^{S168A.UAS.EGFP,Tag:HA} under the control of Scer\GAL4^dpp.blk1 leads to a widening of the Dpp expression domain within the wing disc, without its cells showing an invasive phenotype.

(Blaquiere et al., 2018)

Third instar larval eye-antennal imaginal disc clones expressing yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Act.PU form non-invasive tumors and induce autophagosomes in a cell non-autonomous manner in neighboring clonal tissue, as compared to controls.

(Katheder et al., 2017)

Expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^GMR.PF results in massive eye overgrowth.

(Shalaby et al., 2017)

The expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Bx-MS1096 leads to a severe tumor phenotype in third instar larval wing discs.

(Bunker et al., 2015)

Expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^GMR.PF results in overgrowth and folding of the adult eye.

(Oh et al., 2014)

Expression of wild-type yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} accelerates oocyte border cell migration.

(Lucas et al., 2013)

Expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^hh-Gal4 causes massive overgrowth in the wing disc.

Expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^ptc-559.1 causes overgrowth in the posterior wing pouch, as well as the eye, leg and haltere.

(Chen and Verheyen, 2012)

Wing disc clones expressing yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^αTub84B.PL are overgrown compared to controls.

(Gerhold et al., 2011)

Expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^GMR.PF results in dramatic overgrowth of the eyes.

Clones in the wing disc expressing yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Act5C.PI are larger and rounder than normal.

(Oh and Irvine, 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, enhanceable by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, enhanceable by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

NOT Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-enhanceable by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible by Atg1^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has increased size | adult stage phenotype, suppressible by Atg1^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible | partially by AlaRS^GD8009, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible | partially by AsnRS^RNAi.UAS.cUa, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible | partially by GlyRS^KK107421, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible | partially by AspRS^GD1339, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, suppressible | partially by AsnRS^RNAi.UAS.cUa, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, suppressible | partially by AspRS^GD1339, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, suppressible | partially by GlyRS^KK107421, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, suppressible | partially by AlaRS^GD8009, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has increased occurrence of cell division | larval stage phenotype, suppressible by AsnRS^RNAi.UAS.cUa, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible | partially by hpo^UAS.cUa/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, suppressible | partially by hpo^UAS.cUa/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, suppressible by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, suppressible by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^ptc-559.1, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size phenotype, suppressible by Hipk^UAS.Tag:HA, Scer\GAL4^ptc-559.1

(Chen and Verheyen, 2012)

Scer\GAL4^ptc-559.1, yki^{S168A.UAS.EGFP,Tag:HA} has visible phenotype, suppressible by Hipk^UAS.Tag:HA, Scer\GAL4^ptc-559.1

(Chen and Verheyen, 2012)

yki^{S168A.UAS.EGFP,Tag:HA} has increased cell number | somatic clone phenotype, suppressible by RnrL^A4B5

(Gerhold et al., 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Atg1^{K38Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has increased size | adult stage phenotype, non-suppressible by Atg1^{K38Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has increased size | adult stage phenotype, non-suppressible by Atg6^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has increased size | adult stage phenotype, non-suppressible by Atg13^UAS.Tag:FLAG, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Atg13^UAS.Tag:FLAG, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Atg6^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, non-suppressible by PheRS-m^GD14808, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, non-suppressible by MetRS-m^KK108492, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, non-suppressible by ValRS^GD11206/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, non-suppressible by TrpRS^KK102102/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by MetRS-m^KK108492, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by ValRS^GD11206/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by PheRS-m^GD14808, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by TrpRS^KK102102/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has increased occurrence of cell division | larval stage phenotype, non-suppressible by LysRS^KK101852, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | adult stage phenotype, non-suppressible by LeuRS-m^GD12249, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by LeuRS-m^GD12249, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^Act.PU, yki^{S168A.UAS.EGFP,Tag:HA} has neoplasia | somatic clone | third instar larval stage phenotype, non-suppressible | cell non-autonomous by Atg13^Δ81/Atg13^Δ81

(Katheder et al., 2017)

Scer\GAL4^Act.PU, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | somatic clone | third instar larval stage phenotype, non-suppressible | cell non-autonomous by Atg13^Δ81/Atg13^Δ81

(Katheder et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has abnormal size | adult stage phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Enhancer of

Statement

Reference

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^Bx-MS1096 is an enhancer of increased size | larval stage phenotype of Nkap^GD11807, Scer\GAL4^Bx-MS1096

(Guo et al., 2024)

NOT Enhancer of

Statement

Reference

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^dpp.blk1 is a non-enhancer of abnormal cell migration | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Suppressor of

Statement

Reference

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^dpp.blk1 is a suppressor | partially of neoplasia | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

NOT Suppressor of

Statement

Reference

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^dpp.blk1 is a non-suppressor of abnormal cell migration | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^GMR.PF is a non-suppressor of visible | adult stage phenotype of Ncoa6^GD14752, Scer\GAL4^GMR.PF

(Oh et al., 2014)

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^GMR.PF is a non-suppressor of abnormal size | adult stage phenotype of Ncoa6^GD14752, Scer\GAL4^GMR.PF

(Oh et al., 2014)

Other

Statement

Reference

Acn^UAS.cNa, Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has visible | adult stage phenotype

(Tyra et al., 2020)

Acn^UAS.cNa, Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has decreased size | adult stage phenotype

(Tyra et al., 2020)

Scer\GAL4^GMR.PFa, ThrRS^GD1342, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, TyrRS^GD11353, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

ArgRS^GD14098, Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

CysRS^GD13923, Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

GluProRS^GD11635, Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, SerRS-m^GD12798, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

LysRS^KK101852, Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

HisRS^KK102374, Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

GlnRS^KK109443, Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has lethal - all die before end of P-stage phenotype

(Yeom et al., 2020)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, enhanceable by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

NOT Enhanced by

Statement

Reference

Scer\GAL4^dpp.blk1, yki^{S168A.UAS.EGFP,Tag:HA} has wing disc phenotype, non-enhanceable by Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-enhanceable by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible by Atg1^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible | partially by AsnRS^RNAi.UAS.cUa, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible | partially by AspRS^GD1339, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible | partially by AlaRS^GD8009, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible | partially by GlyRS^KK107421, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has eye disc phenotype, suppressible by AsnRS^RNAi.UAS.cUa, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible | partially by hpo^UAS.cUa/Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^ptc-559.1, yki^{S168A.UAS.EGFP,Tag:HA} has wing disc phenotype, suppressible by Hipk^UAS.Tag:HA, Scer\GAL4^ptc-559.1

(Chen and Verheyen, 2012)

Scer\GAL4^ptc-559.1, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, suppressible by Hipk^UAS.Tag:HA, Scer\GAL4^ptc-559.1

(Chen and Verheyen, 2012)

yki^{S168A.UAS.EGFP,Tag:HA} has wing disc | somatic clone phenotype, suppressible by RnrL^A4B5

(Gerhold et al., 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Atg1^{K38Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Atg13^UAS.Tag:FLAG, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Atg6^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PFa, yki^{S168A.UAS.EGFP,Tag:HA} has eye disc phenotype, non-suppressible by LysRS^KK101852, Scer\GAL4^GMR.PFa

(Yeom et al., 2020)

Scer\GAL4^dpp.blk1, yki^{S168A.UAS.EGFP,Tag:HA} has wing disc phenotype, non-suppressible by Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Enhancer of

Statement

Reference

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^Bx-MS1096 is an enhancer of wing disc | larval stage phenotype of Nkap^GD11807, Scer\GAL4^Bx-MS1096

(Guo et al., 2024)

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^dpp.blk1 is an enhancer of wing disc phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Suppressor of

Statement

Reference

Scer\GAL4^org-1.HN39/yki^{S168A.UAS.EGFP,Tag:HA} is a suppressor | partially of adult heart ventral longitudinal muscle cell | P-stage phenotype of Scer\GAL4^org-1.HN39, rl^HMS00173

(Rose et al., 2022)

Scer\GAL4^org-1.HN39/yki^{S168A.UAS.EGFP,Tag:HA} is a suppressor | partially of adult heart ventral longitudinal muscle cell | P-stage phenotype of Scer\GAL4^org-1.HN39, twi^HMJ03122

(Rose et al., 2022)

Scer\GAL4^org-1.HN39/yki^{S168A.UAS.EGFP,Tag:HA} is a suppressor | partially of adult heart ventral longitudinal muscle cell | P-stage phenotype of Scer\GAL4^org-1.HN39, htl^DN.UAS.cMb

(Rose et al., 2022)

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^org-1.HN39 is a suppressor | partially of adult heart ventral longitudinal muscle cell | P-stage phenotype of Mmmm\ras^N17.UAS, Scer\GAL4^org-1.HN39

(Rose et al., 2022)

Scer\GAL4^Act5C.PI/yki^{S168A.UAS.EGFP,Tag:HA} is a suppressor of wing disc | somatic clone phenotype of Scer\GAL4^Act5C.PI, hpo^UAS.Tag:FLAG

(Oh and Irvine, 2008)

NOT Suppressor of

Statement

Reference

yki^{S168A.UAS.EGFP,Tag:HA}/Scer\GAL4^Tub.PU is a non-suppressor of intestinal stem cell | somatic clone phenotype of lin-28^Δ1

(Chen et al., 2015)

yki^{S168A.UAS.EGFP,Tag:HA}, Scer\GAL4^GMR.PF is a non-suppressor of eye | adult stage phenotype of Ncoa6^GD14752, Scer\GAL4^GMR.PF

(Oh et al., 2014)

Other

Statement

Reference

Acn^UAS.cNa, Scer\GAL4^GMR.PF, yki^{S168A.UAS.EGFP,Tag:HA} has eye phenotype

(Tyra et al., 2020)

Scer\GAL4^Act5C.PI, hpo^UAS.Tag:FLAG, wts^UAS.Tag:MYC, yki^{S168A.UAS.EGFP,Tag:HA} has wing disc | somatic clone phenotype

(Oh and Irvine, 2008)

Additional Comments

Genetic Interactions

Statement

Reference

The size of third instar larval eye-antennal imaginal disc tumors resulting from the clonal expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Act.PU is not decreased when neighboring disc tissue is homozygous for Atg13^Δ81.

(Katheder et al., 2017)

The massive eye overgrowth characteristic for adult flies expressing yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^GMR.PF is further enhanced by combination with a single copy of Utx^Δ, partially suppressed by combination with JMJD5^KO or NO66^KO and not modified by combination with any of the following: Kdm2^KO, JHDM2^KO, Kdm4A^KO, Kdm4B^KO, lid¹⁰⁴²⁴, Jarid2^KO, JMJD7^KO, Df(3R)HSPBAP1-KO, PSR^FM1 and JMJD4^KO.

(Shalaby et al., 2017)

The reduction in total cell number per clone and reduction in number of Dl-positive intestinal stem cells per clone seen in MARCM clones in the intestine of lin-28^Δ1 adults is not rescued by expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^tub.PU.

(Chen et al., 2015)

The small eye phenotype characteristic for adult flies expressing Ncoa6^GD14752 under the control of Scer\GAL4^GMR.PF is not suppressed by co-expression of yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1}, which on its own lead to eye overgrowth.

(Oh et al., 2014)

Expression of hipk^{Scer\UAS.T:Ivir\HA1} suppresses the overgrowth seen when yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} is expressed under the control of Scer\GAL4^ptc-559.1. The phenotype is rescued in all tissues examined, including the wing disc and the eye. Fewer yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} expressing cells are seen, indicating that cell proliferation has been reduced.

(Chen and Verheyen, 2012)

Homozygous RnrL^A4B5 partially suppresses the wing disc overgrowth phenotype seen when yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} mutant clones are generated under the control of Scer\GAL4^αTub84B.PL.

(Gerhold et al., 2011)

Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG} and yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Act5C.PI are recovered in the wing disc.

Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG}, yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} and wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI are not recovered in the wing disc.

(Oh and Irvine, 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type