FlyBase Allele Report: Dmel\mtt[RNAi.UAS]

General Information

Symbol

Dmel\mtt^RNAi.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0239085

Feature type

allele

Associated gene

Dmel\mtt

Associated Insertion(s)

Carried in Construct

P{UAS-mtt.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(Mitri et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Mitri et al., 2009)

Mutagen

in vitro construct

(Mitri et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-mtt.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat corresponding to part of a mtt cDNA.

(Mitri et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

mtt

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal feeding behavior, with Scer\GAL4^Gr66a.PD, mtt^f06268

(Mitri et al., 2009)

abnormal feeding behavior, with Scer\GAL4^NP4288, mtt^f06268

(Mitri et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of mtt^{dsRNA.Scer\UAS.RNAi} using either Scer\GAL4^NP4288 or Scer\GAL4^Gr66a.PD in a mtt^f06268/+ background abolishes the L-canavanine-induced proboscis retraction seen in wild type flies.

(Mitri et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Expression of mtt^{dsRNA.Scer\UAS.RNAi} produces dsRNA which results

(Mitri et al., 2009)

in dsRNA interference (RNAi) of the mtt gene.

(Mitri et al., 2009)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

mtt^{RNAi.UAS.RNAi}

mtt^RNAi.UAS

mtt^{dsRNA.Scer\UAS.RNAi}

mtt^{dsRNA.UAS.RNAi}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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