FB2026_02 , released June 18, 2026
Allele: Dmel\Prosα6TEGFP
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General Information
Symbol
Dmel\Prosα6TEGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0239097
Feature type
allele
Associated gene
Dmel\Prosα6T
Associated Insertion(s)
Carried in Construct
P{Prosα6T-EGFP.M}
Also Known As
Prosα6T-GFP
Key Links
Transgenic product class
wild_type
(Ma et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ma et al., 2002)
Mutagen
in vitro construct
(Ma et al., 2002)
Progenitor genotype
Carried in construct
P{Prosα6T-EGFP.M}
Cytology
Description

Contains the Prosα6T gene, with 0.8kb of upstream sequences and 1.1kb of downstream sequences. The Prosα6T open reading frame is tagged at the C-terminal end with EGFP.

(Ma et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Prosα6T
Encoded product / tool
Prosα6T
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      spermatogenesis
      spermatid
      (Ma et al., 2002)
      spermatozoon
      (Ma et al., 2002)
      epitope tag
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | male
      spermatid cyst
      (Zhong and Belote, 2007)
      elongation stage spermatid
      (Zhong and Belote, 2007)
      individualization stage spermatid
      (Zhong and Belote, 2007)
      spermatozoon
      (Zhong and Belote, 2007)
      Additional Information
      Statement
      Reference

      Prosα6T-GFP becomes prominent in the cytoplasm and nuclei of 64-cell spermatid cysts. Signal persists in the elongated and condensed spermatid nuclei and also in spermatid tail bundles. It is seen in mature sperm heads and tails. Prosα6T-GFP is also found in speckles near the individualization complex.

      (Zhong and Belote, 2007)

      Prosα6TT:AvicGFP-EGFP is expressed only in the testis, and is not expressed until after the second meiotic division. Expression continues through then end of spermatogenesis. Prosα6TT:AvicGFP-EGFP can be observed in the tails of mature sperm cells.

      (Ma et al., 2002)
       
      Marker for
      Reflects expression of
      Prosα6T
      (Zhong and Belote, 2007, Ma et al., 2002)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Prosα6TEGFP rescues Prosα6T1

      (Zhong and Belote, 2007)
      Comments

      The sterility of Prosα6T1 homozygous males is completely rescued by Prosα6TT:Avic\GFP-EGFP.

      (Zhong and Belote, 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Prosα6TEGFP
      Prosα6TT:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (4)