FB2026_02 , released June 18, 2026
Allele: Dmel\su(rdgA)4040
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General Information
Symbol
Dmel\su(rdgA)4040
Species
D. melanogaster
Name
FlyBase ID
FBal0239882
Feature type
allele
Associated gene
su(rdgA)40
Associated Insertion(s)
Carried in Construct
Also Known As
su(40)
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Georgiev et al., 2005)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant photoreceptors show normal electrophysiological responses to light.

      (Georgiev et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      su(rdgA)4040 is a suppressor of visible phenotype of rdgA1

      (Georgiev et al., 2005)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Df(2R)BSC29/su(rdgA)4040 is a suppressor of retina phenotype of rdgA1

      (Georgiev et al., 2012)

      su(rdgA)405/su(rdgA)4040 is a suppressor of retina phenotype of rdgA1

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of phenotype of rdgA2

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of phenotype of rdgA3

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of retina phenotype of rdgB2

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of retina phenotype of trpP365

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of phenotype of rdgAKS60

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of retina phenotype of Arr25

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of retina phenotype of rdgA1

      (Georgiev et al., 2012)

      Df(2R)w45-19g/su(rdgA)4040 is a suppressor of retina phenotype of rdgA1

      (Georgiev et al., 2012)

      Df(2R)Np5/su(rdgA)4040 is a suppressor of retina phenotype of rdgA1

      (Georgiev et al., 2012)

      su(rdgA)4040 is a suppressor of rhabdomere phenotype of trpP365

      (Georgiev et al., 2005)

      su(rdgA)4040 is a suppressor of eye phenotype of rdgA1

      (Georgiev et al., 2005)

      su(rdgA)4040 is a suppressor of rhabdomere phenotype of rdgA1

      (Georgiev et al., 2005)
      NOT Suppressor of
      Statement
      Reference

      su(rdgA)4040 is a non-suppressor of retina phenotype of Nmnat2

      (Georgiev et al., 2012)

      su(rdgA)4040 is a non-suppressor of retina phenotype of norpAP24

      (Georgiev et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      su(rdgA)4040 can block the retinal degeneration seen in rdgA1 mutant eyes for up to 10 days post eclosion.

      su(rdgA)4040 suppresses the retinal degeneration seen in trpP365/+ flies.

      (Georgiev et al., 2012)

      The retinal degeneration phenotype of rdgA1 flies is suppressed if the eyes are also composed entirely of homozygous su(rdgA)4040 tissue (clones generated using the EGUF method).

      The retinal degeneration phenotype of trpP365 flies is rescued by su(rdgA)4040.

      (Georgiev et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: A mutation that suppresses the retinal degeneration phenotype of rdgA1 when the adult eye is composed entirely of homozygous mutant tissue (generated using the EGUF method).

      (Georgiev et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      su(40)
      (Georgiev et al., 2012, Georgiev et al., 2005)
      su(rdgA)4040
      Name Synonyms
      Secondary FlyBase IDs
        References (2)