FlyBase Allele Report: Scer\GAL4[Ilp2.Switch.PK]

General Information

Symbol

Scer\GAL4^{Ilp2.Switch.PK}

Species

S. cerevisiae

Name

FlyBase ID

FBal0240163

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Ilp2-Switch.K}

Also Known As

Dilp2-GS, dilp2-GS-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Karpac et al., 2009)

Progenitor genotype

Carried in construct

P{Ilp2-Switch.K}

Cytology

Description

A 1500bp Ilp2 promoter fragment drives expression of the ligand-inducible GAL4::GS driver.

(Karpac et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

Ilp2

Encoded product / tool

GAL4::GS

binary expression system - small molecule-regulated driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult insulin secreting cell of pars intercerebralis

(Park et al., 2014)

Additional Information

Statement

Reference

ScerGAL4^{Ilp2.Switch.PK} drives mifepristone-inducible adult expression in insulin secreting cells in the medial pars intercerebralis.

(Park et al., 2014)

Marker for

Reflects expression of

Ilp2

(Park et al., 2014)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal stress response | RU486 conditional, with bsk^GD10555

(Karpac et al., 2009)

abnormal stress response | RU486 conditional, with bsk^K53R.UAS

(Karpac et al., 2009)

decreased size | oogenesis, with eya^UAS.cBa

(Abrieux et al., 2020)

increased size | oogenesis, with eya^KK107568

(Abrieux et al., 2020)

Phenotype Manifest In

ovary, with eya^KK107568

(Abrieux et al., 2020)

ovary, with eya^UAS.cBa

(Abrieux et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^{Ilp2.Switch.PK}

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

Open Close