FlyBase Allele Report: Dmel\ci[JF01715]

General Information

Symbol

Dmel\ci^JF01715

Species

D. melanogaster

Name

FlyBase ID

FBal0240324

Feature type

allele

Associated gene

Dmel\ci

Associated Insertion(s)

Carried in Construct

P{TRiP.JF01715}

Also Known As

UAS-Ci RNAi, UAS-ci^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF01715}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF01715

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4²²¹

(Iyer et al., 2013)

abnormal neuroanatomy, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

visible | somatic clone, with Scer\GAL4^{Act5C.CoinFLP-FRT}

(Bosch et al., 2015)

Phenotype Manifest In

abdominal anterior ventral multidendritic neuron vdaa, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

eye | somatic clone, with Scer\GAL4^{Act5C.CoinFLP-FRT}

(Bosch et al., 2015)

larval dorsal multidendritic neuron ddaC, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

larval dorsal multidendritic neuron ddaD, with Scer\GAL4²²¹

(Iyer et al., 2013)

larval ventral multidendritic neuron vdaB, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

Detailed Description

Statement

Reference

Expression of ci^JF01715 using P{CoinFLP-GAL4} and Scer\FLP1^ey.PN to stochastically generate patches of cells in the eye expressing Scer\GAL4^{Act5C.CoinFLP-FRT} results in overgrowth especially in the anterior part of the eye.

(Bosch et al., 2015)

Expressing ci^JF01715 under the control of Scer\GAL4^ey.PH does not cause any overt eye overgrowth.

(Da Ros et al., 2013)

Expression of ci^JF01715 in C-IV neurons under the control of Scer\GAL4^ppk.1.9 results in a reduction in total dendritic length in ddaC, v'ada and vdaB neurons. The total number of dendritic branches is also reduced in ddaC and v'ada neurons.

Expression of ci^JF01715 in C-I neurons under the control of Scer\GAL4²²¹ results in ddaD neurons that have an increased number of dendritic branches compared to controls.

(Iyer et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

ci^JF01715, Scer\GAL4^ey.PH is an enhancer of visible | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Suppressor of

Statement

Reference

ci^JF01715/Scer\GAL4^109-30 is a suppressor of hyperplasia phenotype of boi^e01708

(Hartman et al., 2010)

Phenotype Manifest In

Enhancer of

Statement

Reference

ci^JF01715, Scer\GAL4^ey.PH is an enhancer of eye phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Suppressor of

Statement

Reference

ci^JF01715/Scer\GAL4^109-30 is a suppressor of follicle stem cell phenotype of boi^e01708

(Hartman et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

ci^JF01715 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH, resulting in flies with secondary eye growths within the thorax and abdomen. The phenotype is seen with 100% penetrance.

(Da Ros et al., 2013)

Expression of ci^JF01715 under the control of Scer\GAL4^109-30 suppresses the boi^e01708 mutant follicle stem cell phenotype.

(Hartman et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

28984

y¹ v¹; P{TRiP.JF01715}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ci^JF01715

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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