FlyBase Allele Report: Scer\GAL4[109-30]

ScerGAL4^109-30 drives expression at the dorsal midline of the embryo, in the embryonic PNS, in a segmentally repeated pattern in the larval ventral nerve cord, and in stalk cells, polar follicle cells, and follicle stem cells during oogenesis.

(Bloomington Drosophila Stock Center, 2017, Younger, 2001.2)

Drives expression in follicle cells and follicle stem cells during oogenesis.

(FlyBase Curators, 2017)

ScerGAL4^109-30 drives expression in follicle stem cells and in early follicle cells.

(Ulmschneider et al., 2016)

ScerGAL4^109-30 drives expression in posterior escort cells, in follicle stem cells and in early follicle cells.

(Johnston et al., 2016)

ScerGAL4^109-30 drives expression in the follicle cells in the germarium and the early egg chamber until oogenesis stage S3.

(Urwyler et al., 2012)

Expressed in the embryonic dorsal midline and PNS, the larval ventral nerve cord and segmentally in the nervous system, and in stalk cells, follicle cells at the poles of the egg chamber and in the precursors to the follicle cells in the germarium.

(Kester and Nambu, 2011)

ScerGAL4^109-30 drives expression in the embryonic dorsal midline and peripheral nervous system, the larval ventral nerve cord and segmentally in the nervous system, and in stalk cells, follicle cells at the poles of the egg chamber and the precursors to the follicle cells in the germarium.

(Younger, 2001.2)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | oogenesis, with Ae2^GD2397

(Benitez et al., 2019)

abnormal size | oogenesis, with Ae2^HMJ30143

(Benitez et al., 2019)

abnormal stress response, with Hsap\KCNJ2^UAS.EGFP

(Kenmoku et al., 2016)

hyperplasia, with boi^EY09847

(Hartman et al., 2010)

increased body weight | adult stage, with Hnf4^UAS.cPa

(Almeida-Oliveira et al., 2021)

increased cell number | oogenesis, with gro^AA.UASp

(Johnston et al., 2016)

increased cell number | oogenesis, with N^intra.GS.UAS

(Johnston et al., 2016)

increased cell number | oogenesis, with Six4^{UAS.ORF.GW.Tag:HA}

(Johnston et al., 2016)

increased cell number | oogenesis | somatic clone, with Six4¹⁰⁸

(Johnston et al., 2016)

lethal - all die before end of larval stage, with Cdc42^UAS.cLa

(Younger, 2001.2)

lethal - all die before end of larval stage, with N^UAS.cSa

(Younger, 2001.2)

some die during larval stage, with Cdc42^UAS.cLa

(Younger, 2001.2)

some die during larval stage, with N^UAS.cSa

(Younger, 2001.2)

Phenotype Manifest In

basal stalk, with Ae2^GD2397

(Benitez et al., 2019)

basal stalk, with Ae2^HMC03399

(Ulmschneider et al., 2016)

basal stalk, with Ae2^HMJ30143

(Benitez et al., 2019)

basal stalk, with Ae2^KK100095

(Ulmschneider et al., 2016)

basal stalk, with btl::Egfr^λ.UAS

(Johnston et al., 2016)

basal stalk, with gro^AA.UASp

(Johnston et al., 2016)

basal stalk, with gro^DD.UASp

(Johnston et al., 2016)

basal stalk, with gro^HMS01506

(Johnston et al., 2016)

basal stalk, with gro^UASp.cCa

(Johnston et al., 2016)

basal stalk, with N^intra.GS.UAS

(Johnston et al., 2016)

basal stalk, with N^JF01356

(Johnston et al., 2016)

basal stalk, with Nhe2^HMC03243

(Ulmschneider et al., 2016)

basal stalk, with Nhe2^KK102518

(Ulmschneider et al., 2016)

basal stalk, with Nhe2^UAS.cGa

(Ulmschneider et al., 2016)

basal stalk, with ptc^JF03223

(Ulmschneider et al., 2016)

basal stalk, with Six4^HM05254

(Johnston et al., 2016)

basal stalk, with Six4^{UAS.ORF.GW.Tag:HA}

(Johnston et al., 2016)

egg chamber, with hh^HMS00492

(Sahai-Hernandez and Nystul, 2013)

egg chamber, with N^JF01356

(Johnston et al., 2016)

egg chamber, with Six4^HM05254

(Johnston et al., 2016)

female germline cyst, with Nhe2^HMC03243

(Ulmschneider et al., 2016)

female germline cyst, with Nhe2^KK102518

(Ulmschneider et al., 2016)

female germline stem cell | oogenesis, with Nhe2^HMC03243

(Ulmschneider et al., 2016)

female germline stem cell | oogenesis, with Nhe2^KK102518

(Ulmschneider et al., 2016)

follicle cell, with Ae2^HMC03399

(Ulmschneider et al., 2016)

follicle cell, with btl::Egfr^λ.UAS

(Johnston et al., 2016)

follicle cell, with gro^AA.UASp

(Johnston et al., 2016)

follicle cell, with gro^HMS01506

(Johnston et al., 2016)

follicle cell, with N^JF01356

(Johnston et al., 2016)

follicle cell, with Nhe2^HMC03243

(Ulmschneider et al., 2016)

follicle cell, with Nhe2^KK102518

(Ulmschneider et al., 2016)

follicle cell, with Nhe2^UAS.cGa

(Ulmschneider et al., 2016)

follicle cell, with Nhe2^{UAS.E358I.Tag:HA}

(Ulmschneider et al., 2016)

follicle cell, with Six4^HM05254

(Johnston et al., 2016)

follicle cell, with Six4^{UAS.ORF.GW.Tag:HA}

(Johnston et al., 2016)

follicle stem cell, with Ae2^HMC03399

(Ulmschneider et al., 2016)

germarium, with Ae2^HMC03399

(Ulmschneider et al., 2016)

germarium, with gro^HMS01506

(Johnston et al., 2016)

germarium, with hh^HMS00492

(Sahai-Hernandez and Nystul, 2013)

germarium, with Nhe2^HMC03243

(Ulmschneider et al., 2016)

germarium, with Nhe2^KK102518

(Ulmschneider et al., 2016)

germarium, with Nhe2^UAS.cGa

(Ulmschneider et al., 2016)

germarium, with Nhe2^{UAS.E358I.Tag:HA}

(Ulmschneider et al., 2016)

ovariole, with hh^HMS00492

(Sahai-Hernandez and Nystul, 2013)

stalk follicle cell, with boi^EY09847

(Hartman et al., 2010)

stalk follicle cell, with btl::Egfr^λ.UAS

(Johnston et al., 2016)

stalk follicle cell, with gro^AA.UASp

(Johnston et al., 2016)

stalk follicle cell, with N^intra.GS.UAS

(Johnston et al., 2016)

stalk follicle cell, with Nhe2^HMC03243

(Ulmschneider et al., 2016)

stalk follicle cell, with Nhe2^KK102518

(Ulmschneider et al., 2016)

stalk follicle cell, with Six4^{UAS.ORF.GW.Tag:HA}

(Johnston et al., 2016)

Detailed Description

Statement

Reference

Inhibition (using Hsap\KCNJ2^UAS.EGFP) of Scer\GAL4^109-30 cells, in combination with a Gal80[ts] transgene to restrict expression to the adult stage, results in reduced survival rates following infection with Ecc15, compared to controls.

(Kenmoku et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

N^intra.GS.UAS, Scer\GAL4^109-30 has increased cell number | oogenesis phenotype, non-suppressible by Six4^HM05254, Scer\GAL4^109-30

(Johnston et al., 2016)

Suppressor of