FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\PlexBUAS.Tag:MYC
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General Information
Symbol
Dmel\PlexBUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0240482
Feature type
allele
Associated gene
Dmel\PlexB
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-PlexB}
Also Known As
UAS-myc-plexB, Myc-PlexB
Key Links
Transgenic product class
wild_type
(Ayoob et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ayoob et al., 2006)
Mutagen
in vitro construct
(Ayoob et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Myc-PlexB}
Cytology
Description

UASt regulatory sequences drive expression of PlexB coding sequences tagged with Tag:MYC at the N-terminal.

(Ayoob et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
PlexB
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Charcot-Marie-Tooth disease type 2D
      modeled by GlyRSP234KY-2.UAS
      (Grice et al., 2018)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PU/PlexBUAS.Tag:MYC rescues PlexBKG00878

      (Wu et al., 2011)
      Comments

      Expression of PlexBUAS.Tag:MYC under the control of Scer\GAL4PlexB-MI15559-TG4.1 almost completely rescues prior to eclosion lethality and partially rescues after eclosion lethality phenotypes of PlexBKG00878/PlexBMI15559-TG4.1 transheterozygotes.

      (Xie et al., 2019)

      Expression of plexBScer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav.PU fully rescues the longitudinal connective defects seen in plexBKG00878 embryos.

      (Wu et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      PlexBScer\UAS.T:Hsap\MYC
      PlexBUAS.Tag:MYC
      plexBScer\UAS.T:Hsap\MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (6)