FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mlp84BP20
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General Information
Symbol
Dmel\Mlp84BP20
Species
D. melanogaster
Name
FlyBase ID
FBal0240774
Feature type
allele
Associated gene
Dmel\Mlp84B
Associated Insertion(s)
P{lacW}Mlp84BP20
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - genetic evidence

    (Clark et al., 2007)
    Mutagen
    Progenitor genotype
    P{lacW}Alhj8C8
    (Clark et al., 2007)
    Associated Insertion(s)
    P{lacW}Mlp84BP20
    Cytology
    Description

    Mobilisation of the P{lacW}Alhj8C8 progenitor insertion has resulted in a new P-element insertion in an Mlp84B intron at base-pair 493.

    (Clark et al., 2007)
    Allele components
    Component
    Use(s)
    Inserted element
    P{lacW}
    Encoded product / tool
    lacZ
    Tagged with
    Tag:NLS(P)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Most of the Mlp84BP20/Df(3R)dsx2M hemizygotes die as pupae. As a result of an apparent failure of body wall muscle contraction during puparium formation, these mutants exhibit a larger length/width ratio of the pupal cases than wild-types. The surviving adults are not healthy and usually die within one week of eclosion.

        (Clark et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        Mlp84BP20/Df(3R)dsx2M has lethal | adult stage phenotype, enhanceable by sls[+]/slsj1D7

        (Clark et al., 2007)
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        Mlp84BP20/Df(3R)dsx2M has pupal cuticle phenotype, enhanceable by sls[+]/slsj1D7

        (Clark et al., 2007)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        slsj1D7 heterozygosity reduces the viability of Mlp84BP20/Df(3R)dsx2M mutants to zero. slsj1D7 heterozygosity also exacerbates the pupal case elongation associated with Mlp84BP20/Df(3R)dsx2M.

        (Clark et al., 2007)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Mlp84BP20/Df(3R)dsx2M is rescued by Mlp84B+t10.5

        (Clark et al., 2007)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Mlp84BP20
        mlp84BP20
        (Clark et al., 2007)
        mlpP20
        (Clark et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)