FlyBase Allele Report: Dmel\Arc1[esm113]

General Information

Symbol

Dmel\Arc1^esm113

Species

D. melanogaster

Name

FlyBase ID

FBal0240956

Feature type

allele

Associated gene

Dmel\Arc1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Mattaliano et al., 2007)

Progenitor genotype

Cytology

Description

Imprecise excision of P{GT1}BG01371 deletes some of the 5' coding region of Arc1.

(Mattaliano et al., 2007)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates tauopathy

modeled by Hsap\MAPT^R406W.UAS

(Schulz et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate

(Keith et al., 2021)

abnormal developmental rate (with Arc1^E8)

(Keith et al., 2021)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Arc1^esm113 is a non-enhancer of visible | adult stage phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

Suppressor of

Statement

Reference

Arc1^esm113 is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

Arc1^esm113 is a suppressor | partially of increased cell death | adult stage phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

NOT Suppressor of

Statement

Reference

Arc1^esm113 is a non-suppressor of visible | adult stage phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Arc1^esm113 is a non-enhancer of eye phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

Suppressor of

Statement

Reference

Arc1^esm113 is a suppressor | partially of adult CNS neuron | decreased number phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

NOT Suppressor of

Statement

Reference

Arc1^esm113 is a non-suppressor of eye phenotype of Hsap\MAPT^R406W.UAS, Scer\GAL4^elav-C155

(Schulz et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

37531

w^*; Arc1^esm113

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Arc1^esm113

(Schulz et al., 2023, Keith et al., 2021, Mattaliano et al., 2007)

Arc^esm13

(Vaziri et al., 2020)

darc1^esm113

(Ashley et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close