FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\witd02492
Open Close
General Information
Symbol
Dmel\witd02492
Species
D. melanogaster
Name
FlyBase ID
FBal0241138
Feature type
allele
Associated gene
Dmel\wit
Associated Insertion(s)
P{XP}witd02492
Carried in Construct
Also Known As
d02492
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{XP}witd02492
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{XP}
    Regulatory region(s)
    UAS
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        exacerbates  childhood spinal muscular atrophy
        modeled by Smn73Ao
        (Chang et al., 2008)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Other
        Statement
        Reference

        Scer\GAL4Tub.PU, Smn73Ao, witd02492/wit[+] has lethal | dominant phenotype

        (Chang et al., 2008)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        witd02492 suppresses the pupal lethality caused by expression of SmndsRNA.FL.Scer\UAS.WIZ under the control of Scer\GAL4tub.PU : the proportion of pupae reaching a pigmented stage is increased.

        (Sen et al., 2013)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        d02492
        (Sen et al., 2013)
        witd02492
        Name Synonyms
        Secondary FlyBase IDs
          References (2)